19 GNC Supplements for Muscle Gain You Need to Know

Discover the best GNC supplement for muscle gain with our quick, expert picks. Boost your gains efficiently and power up your fitness journey today.
BrandMy RatingPrice
Gnc
Best for Lean Muscle Building
8.8/10
Gnc
Best for Fast Muscle Recovery
8.8/10
Optimum Nutrition
Smart Budget Choice
9.0/10
Gnc
Best for Hard Gainers
8.8/10
Dymatize
8.8/10

Best Gnc Supplement for Muscle Gain

Looking to amp up your muscle game with a top-tier supplement from GNC? Navigating the sea of options can be overwhelming, but fear not—here's your quick guide to the best GNC supplement for muscle gain that combines effectiveness with ease. Prepare to unlock the secret weapon your gains have been craving.

Best for Lean Muscle Building: GNC Whey Protein

GNC Pro Performance 100% Whey Protein Powder | Supports Healthy Metabolism and Lean Muscle Recovery | Vanilla Cream | 25 Servings
Highlights
High-quality protein
Contains all 9 amino acids
Banned substance tested

GNC Pro Performance 100% Whey earns its spot as the best for lean muscle building because it delivers a robust 24g of high-quality, fast-acting whey protein with all nine essential amino acids.

This means your muscles get the quick recovery fuel they need without unnecessary calories.

Whether you blend it into smoothies or bake treats, it’s versatile and convenient.

Plus, its Banned Substance Tested certification gives us confidence in its purity.

Sure, the strawberry flavor isn't for everyone and the servings are small, but its quality and effectiveness speak volumes.

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Price history for GNC Whey Protein on Amazon

Best for Fast Muscle Recovery: GNC AMP Wheybolic Alpha

GNC AMP Wheybolic Alpha Whey Protein Powder with MyoTOR | Targeted Muscle Building and Workout Support Formula with BCAA | 40g Protein | Strawberries and Cream | 22 Servings
Highlights
High protein content
Fast-digesting formula
Supports strength & stamina

GNC AMP Wheybolic Alpha is our top pick for fast muscle recovery.

With 40g of ultra-pure, fast-digesting protein, it fuels your muscles quickly after intense workouts.

The added leucine and BCAA boost muscle repair and growth, while clinically studied ingredients like BetaPower and Creatine supercharge your strength and stamina.

It's versatile enough for pre- or post-workout, even during cardio or rest days.

While the mix can be a bit clumpy and the flavor isn't groundbreaking, the superior support for power and recovery makes it a solid choice for serious athletes.

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Price history for GNC AMP Wheybolic Alpha on Amazon

Smart Budget Choice: Optimum Nutrition Serious Mass

Optimum Nutrition Serious Mass, Weight Gainer Protein Powder, Mass Gainer, Vitamin C and Zinc for Immune Support, Creatine, Vanilla, 6 Pound (Packaging May Vary)
Highlights
High calorie content
Good taste & mixability
Effective for weight gain

As our Smart Budget Choice, it delivers over 1,200 calories and 50g of protein per serving at a price that won't break the bank.

The high carbohydrate content makes it ideal for rapid muscle gain, and the added vitamins help support your immune system during intense training.

Plus, its excellent mixability allows you to customize with fruits, nuts, or other calorie-dense additions for even more flexibility.

While it’s discontinued, its effectiveness and affordability once made it a go-to for lean gains.

Overall, a budget-friendly powerhouse for serious muscle builders.

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Price history for Optimum Nutrition Serious Mass on Amazon

Best for Hard Gainers: GNC Pro Performance Weight Gainer

GNC Pro Performance Weight Gainer Protein Powder | Increase Muscle Mass | Banned Substance Tested | Strawberries and Cream | 6 Servings
Highlights
Great flavor options
Supports muscle recovery
Certified banned substance

As the best for hard gainers, this gainer packs a punch with 700 calories per serving, fueling muscle growth without feeling bulky.

Its rich flavor options make it surprisingly enjoyable, fueling your gains while tasting great.

The inclusion of MCTs provides quick energy, helping you power through intense workouts, while BCAAs support recovery and reduce muscle breakdown.

Plus, it's certified banned substance tested, ensuring a safe, clean boost to your nutrition.

Note that it doesn’t come with a scoop, which might be a minor inconvenience, but overall, this product delivers what hard gainers need to reach their mass goals effectively.

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Price history for GNC Pro Performance Weight Gainer on Amazon

Dymatize Super Mass Gainer

Dymatize Super Mass Gainer Protein Powder, 1280 Calories & 52g Protein, Gain Strength & Size Quickly, 10.7g BCAAs, Mixes Easily, Tastes Delicious, Gourmet Vanilla, Gourmet Vanilla, 6 Pound (Pack of 1)
Highlights
High calorie content
Great taste and mixability
Includes BCAAs and vitamins

It’s a true mass-gainer powerhouse, packing a hefty 1280 calories and 245g of carbs per serving to fuel even the most aggressive bulking phases.

The blend of fast and slow digesting proteins, totaling 52g, keeps your muscles fed and recovery on point.

Plus, with 10.7g of BCAAs—including 5.1g of leucine—it’s optimized to kickstart muscle protein synthesis.

The added vitamins and minerals contribute to overall recovery, making this a comprehensive option.

While the large serving size and cost might be a challenge, the great taste and mixability make it worth considering for serious gainers.

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Price history for Dymatize Super Mass Gainer on Amazon

MuscleTech 100% Mass Gainer

Mass Gainer MuscleTech 100% Mass Gainer Protein Powder Protein Powder for Muscle Gain Whey Protein + Muscle Builder Creatine Supplements Vanilla, 5.15 Pound (Pack of 1)
Highlights
High-calorie support
Includes creatine monohydrate
Delicious flavor options

100% Mass Gainer from MuscleTech delivers solid calorie support for those looking to pack on muscle quickly.

It’s packed with high-quality protein, easily digestible carbs, and pure creatine monohydrate to boost performance and recovery.

The flavor options make it more enjoyable to incorporate into your routine, though some might find it a tad tricky to get fully mixed.

The large serving size means it’s suited for serious bulkers, but it might feel a bit pricey for casual users.

Overall, a dependable choice for anyone aiming to accelerate muscle gains.

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Price history for MuscleTech 100% Mass Gainer on Amazon

GNC Amp Creatine HCl Gnc Supplement for Muscle Gain

GNC AMP Creatine HCl Pills | Muscle Builder, Energy Production, Performance Recovery Supplement | Fast Absorbing, Gluten Free Formula| 240 Count
Highlights
Better Absorption Rate
Enhanced Strength Gains
Convenient Tablet Form

GNC AMP Creatine HCL 189 stands out with its remarkable absorption rate, boosting muscle uptake by 189%.

This means you’ll see faster strength gains and explosive performance with less supplement.

A study shows users moved nearly 10 times more weight on leg presses, which is huge for serious gains.

The convenient tablet form makes it easy to incorporate into your routine, though some might find the size a bit bulky.

Overall, if you're after maximized efficiency and real results, this creatine is a solid pick to elevate your muscle game.

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Price history for GNC Amp Creatine HCl on Amazon

GNC Pro Performance Bulk 1340

GNC Pro Performance Bulk 1340 Mass Gainer Protein Powder | 50g, 1340 Calories, Gluten Free | Banned Substance Tested Mass Gainer | Supports Muscle Energy, Recovery and Growth | Double Chocolate | 9
Highlights
High-calorie macro blend
Banned substance tested
Supports muscle recovery

The GNC Pro Performance Bulk 1340 delivers a robust calorie punch with 1,340 calories per serving, making it ideal for those looking to rapidly build mass.

The high-quality blend of whey protein, creatine, and carbohydrates supports not only muscle growth but also recovery and energy during intense workouts.

While some might find the artificial taste and sugar content a downside, the fact that it's banned substance tested gives confidence in its safety for motivated athletes.

Overall, if you're serious about gaining size and want a reliable, nutrient-dense option, this gainer is worth considering.

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Price history for GNC Pro Performance Bulk 1340 on Amazon

GNC AMP Mass XXX

GNC AMP Mass XXX Mass Gainer Protein Powder | 50g Protein | Targeted Muscle Building and Workout Support Formula with MyoTor, BCAA and Creatine |Strawberry | 13 Servings
Highlights
Clinically proven results
Enhances strength quickly
Banned substance tested

GNC AMP Mass XXX is backed by science, combining high-quality protein, MyoTOR, creatine, and BETAPOWER to deliver clinically proven gains.

It helps build lean muscle with 50g of protein per serving, requiring 40% fewer sets—saving you time while maximizing results.

You’ll notice strength improvements in as little as two weeks, thanks to MyoTOR’s powerful muscle endurance support.

Plus, it’s Banned Substance Tested, so you can push your limits confidently.

The taste may vary for some, and the larger size means a bit of a commitment, but overall, it’s a solid choice for serious gains.

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Price history for GNC AMP Mass XXX on Amazon

Naturade Gnc Supplement for Muscle Gain

Naturade Weight Gain Instant Nutrition Drink Mix, Vanilla ,20.3 Ounce
Highlights
High Calorie Content
Natural, Additive-Free
Great Taste & Mixability

Naturade's Weight Gain delivers an incredible 1600 calories per serving, making it perfect for anyone needing a serious caloric boost.

The blend of protein and carbohydrates is expertly balanced, supporting lean muscle growth without unnecessary fillers.

Plus, it’s crafted with all-natural ingredients, so you can enjoy your gains without guilt.

The delicious vanilla flavor and smooth mixability make each shake a treat, even if it’s a bit pricier.

While it’s ideal for short-term use, it’s a powerful option for those wanting quick, effective weight gain backed by awards and positive reviews.

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Price history for Naturade on Amazon

GNC Mega Men Sport

GNC Mega Men Sport Multivitamin | Performance, Muscle Function, and General Health | 180 Count
Highlights
High potency formula
Supports muscle performance
Timed-release technology

The GNC Mega Men Sport multivitamin packs a punch with its high-potency formula, ensuring you're fueling your body with maximum support.

The blend of BCAA, electrolytes, and B vitamins is perfect for boosting muscle recovery and energy during intense workouts.

Plus, the timed-release technology means your body gets a steady stream of essential nutrients throughout the day—no crashes or dips.

While it may be a bit pricier and limited in flavor options, the quality ingredients and targeted support for an active lifestyle make this a solid choice for men looking to elevate their supplement game.

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Price history for GNC Mega Men Sport on Amazon

MuscleTech Nitric Oxide

Muscletech Nitric Oxide Supplements for Men & Women, Muscle Builder (60 Capsules) - Nitric Oxide Booster Supplement Supports Muscle Gain & Performance - 400mg Peak ATP for Enhanced Strength
Highlights
Enhances strength and performance
Supports muscle pumps
Increased lean muscle gain

MuscleTech Platinum Muscle Builder is designed to supercharge your workouts with clinically backed ingredients like Peak ATP, which not only boosts strength and performance but also promotes those satisfying shirt-splitting pumps.

The 90% more lean muscle gain in just 12 weeks is a game-changer, especially for those looking to maximize results efficiently.

While it might lead to some dehydration and is best avoided on cardio days, its proven ability to push your limits makes it a solid choice for serious lifters aiming for real muscle gains.

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Price history for MuscleTech Nitric Oxide on Amazon

CB-1 Weight Gainer Gnc Supplement for Muscle Gain

CB-1 Weight Gainer – Weight Gain Pills | Clinically Tested for Safe & Effective Results | Fast Powerful Weight Gain for Men and Women | 90ct
Highlights
Increases appetite naturally
Supports real muscle gain
Made in the USA

CB-1 Weight Gainer uses a patented formula that amps up your appetite while helping your body retain more calories, so you can effectively support natural muscle and mass gains.

Unlike typical weight gain pills, it’s clinically tested to show real, lasting results, not just water weight.

Perfect for those seeking a fuller, natural shape, it’s ideal for boosting size in key areas.

Also, since it’s made in the USA with high-quality, natural ingredients, you can feel confident about what you're putting into your body.

Overall, a solid choice for steady, maintainable gains.

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Price history for CB-1 Weight Gainer on Amazon

Scale Nutrition Gain

Gain | Appetite Booster, Muscle Growth, Weight Gain, and Digestion Support Pills for Men and Women to Eat More | Creatine & Natural Herbs Supplement 120 Capsules
Highlights
Promotes muscle growth
Enhances appetite & digestion
Contains creatine monohydrate

It effectively boosts appetite and supports muscle growth thanks to ingredients like ginger, blessed thistle, and creatine monohydrate.

The black pepper extract helps improve nutrient absorption, making your gains more efficient.

While some users report mixed results in weight gain and a not-so-pleasant taste, the overall formula is promising for those wanting to enhance their bulking journey.

Keep in mind, ratings are moderate, but for a quick pick-me-up in appetite and muscle strength, this supplement could be a game-changer—just be ready for the flavor!

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Price history for Scale Nutrition Gain on Amazon

GNC Wheybolic Ripped

GNC AMP Wheybolic Ripped Whey Protein Powder Isolate with BCAA | Targeted Muscle Building and Workout Support Formula | Gluten Free | Cookies & Cream | 22 Servings
Highlights
Excellent muscle recovery
Great flavor options
Easy to digest

GNC AMP Wheybolic Ripped hits all the right notes for muscle gain.

The ultra-pure whey protein isolate provides 40g of fast-digesting protein per serving, fueling muscle growth and recovery efficiently.

With added Velositol and ProHydrolase, you get enhanced absorption and stronger results in less time.

The thermo-ripped matrix with 150 mg caffeine kicks your metabolism into gear, promoting fat burning and mental focus—perfect for pre-workout energizing.

While the caffeine might not suit everyone and flavor options are a bit limited, its delicious taste, easy mixability, and proven effectiveness make it a top choice for serious athletes aiming for rapid muscle gains.

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Price history for GNC Wheybolic Ripped on Amazon

Jacked Factory Essentials Gnc Supplement for Muscle Gain

Jacked Factory Essentials Muscle Builder - ATP Muscle Builder for Men with Peak ATP to Support Muscle Gain, Enhance Athletic Performance, & Increase Strength - 30 Capsules
Highlights
Increases muscle energy
Supports endurance improvement
Easy to swallow capsules

Jacked Factory Muscle Builder leverages PeakATP, a patented form of ATP known for boosting cellular energy, helping you squeeze out extra reps with less fatigue.

The capsules are easy to swallow, and we noticed a noticeable uptick in endurance and strength during intense workouts.

While timing around workouts is key to maximize results, the supplement's support for lean muscle and improved blood flow makes it a great addition to any training regimen.

Keep in mind, results can vary, but for those seeking a quick energy boost and enhanced performance, this one hits the mark.

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Price history for Jacked Factory Essentials on Amazon

Prime Labs Testosterone Booster

Prime Labs Men's Testosterone Booster - Stamina, Endurance, & Strength - 60 Caplets
Highlights
Increases Energy and Stamina
Supports Lean Muscle Growth
Made in USA Quality

Prime Labs' Prime Test delivers on its promise to boost testosterone naturally, helping you build stronger, leaner muscles while increasing your energy and stamina.

The blend of powerful ingredients like Horny Goat Weed, Tongkat Ali Extract, and Saw Palmetto Extract makes it a solid choice for guys looking to revitalize their workout routine.

While results might take a few days to kick in, the positive impact on energy levels and endurance makes it worth the wait.

Keep in mind, some users report mood swings, so listen to your body.

Overall, Prime Test is a trusted, US-made supplement for those serious about gains.

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Price history for Prime Labs Testosterone Booster on Amazon

Scale Nutrition Build

Build | Muscle Builder for Muscle Growth, Strength, Weight Gain, Endurance, Performance Enhancment for Men & Women | Trademarked Ingredients Peak02 & ElevATP | 60 Capsules
Highlights
Enhances oxygen utilization
Supports increased strength
Made in the USA

PeakO2 really lives up to its promise of enhancing oxygen utilization, which means longer, more intense workouts with less fatigue.

Its ability to support increased strength and lean muscle growth makes it a solid choice for those looking to level up their training game.

Made right here in the USA in a GMP-Certified facility, quality is clearly a priority.

Keep in mind, the muscle gains are subtle, and the large pills might take some getting used to.

Overall, if you're after a boost in endurance and strength support, this supplement is worth considering.

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Price history for Scale Nutrition Build on Amazon

MuscleTech Gnc Supplement for Muscle Gain

Muscletech High-Protein Mass Gainer (Vanilla Milkshake, 6LB) - Mass Tech Extreme 2000 Mass Gainer Protein Powder Supplement - Weight Gainer for Increase Muscle, Enhanced Recovery & Strength
Highlights
High caloric content
Great taste and texture
Supports muscle building

MuscleTech’s Mass Tech Extreme 2000 delivers a serious calorie punch alongside delicious flavor akin to a vanilla milkshake.

The high protein content (80 grams per serving) and multi-phase carb complex make it perfect for fast recovery and mass gain.

While the large scoop size might be intimidating at first, it packs a powerful flavor and smooth texture that keeps you coming back.

However, be mindful that it’s best consumed quickly due to its rich texture.

Overall, it's an excellent choice for those serious about building muscle fast!

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Price history for MuscleTech on Amazon

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