20 Lion’s Mane Brands to Boost Your Brain Power

Discover the best lion's mane brands for sharp focus and natural vitality. Uncover top picks to elevate your supplement game effortlessly.
BrandMy RatingPrice
Maryruth Organics
Best Bang for Your Buck
9.0/10
Host Defense
Best for Focus & Clarity
9.2/10
Freshcap Mushrooms
Best Organic Mushroom Extracts
8.8/10
New Age
Best for Immune Support
8.8/10
The Genius Brand
8.6/10

Best Lion's Mane Brands

Looking to unlock sharper focus and boost your brainpower? Dive into our curated list of the best lion's mane brands, where quality meets reliability in the realm of cognitive enhancement. Discover top-tier products designed to energize your mind with pure potency and trustworthy purity.

Best Bang for Your Buck: MaryRuth Lions Mane

MaryRuth Organics Lions Mane Mushroom Supplement, Upto 2 Month Supply, Nootropic USDA Organic Lions Mane Extract Nervine Herbal Liquid Drops, Brain Health Non-GMO Vegan Alcohol Free Tincture, 1 Fl Oz
Highlights
Organic and vegan formula
Easy-to-take liquid drops
Supports cognitive health

As our Best Bang for Your Buck, it offers a substantial 2-month supply packed with organic, vegan-friendly Lion’s Mane in a convenient liquid form.

The high customer ratings and numerous reviews tell us it’s trusted by many for supporting cognitive health and focus.

Plus, it’s free from common allergens and artificial junk, making it a clean choice for everyday use.

The liquid drops are easy to take—just shake, drop, and go—perfect for busy lifestyles.

Overall, a great value for those seeking quality and quantity in one bottle.

Be sure to also check out the best lion's mane tea for more options! Also, here is the price history so you know exactly when to buy!

Price history for MaryRuth Lions Mane on Amazon

Best for Focus & Clarity: Host Defense Mushrooms

Host Defense Mushrooms Lion's Mane - Brain Health Support Supplement for Focus & Memory Function - Immune & Nervous System Support Supplement - 120 Capsules (60 Servings)*
Highlights
Supports brain health
Organic, non-GMO
Enhanced mental clarity

Host Defense's Lion's Mane is carefully crafted for enhanced focus and mental clarity.

As a product designed specifically for cognitive support, it features a potent blend of organic, non-GMO mushroom mycelium grown right here in the USA.

The trusted brand founder, Paul Stamets, backs the quality, ensuring you're getting a reliable and effective supplement.

Its targeted formulation supports not just brain health but also immune and nervous system wellness.

Ideal for anyone prioritizing sharpness and mental agility, this supplement is a smart choice for your daily routine.

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Price history for Host Defense Mushrooms on Amazon

Best Organic Mushroom Extracts: FreshCap Lions Mane

FreshCap Lions Mane Supplement Capsules 14,000mg - Lion's Mane Mushroom Capsules, Lions Mane Extract, Lion Mane Mushroom Supplement, Ayurveda Lions Mane Mushroom Capsules (120 Capsules)
Highlights
High potency (14,000mg raw mushroom)
Organic, no fillers
Easy daily use

FreshCap Mushrooms’ Lion’s Mane capsules truly stand out as "Best Organic Mushroom Extracts" thanks to their triple-extracted, premium quality formula.

Each capsule delivers a whopping 14,000mg of raw mushroom equivalent, ensuring you get maximum potency with every dose.

Crafted from 100% whole fruiting bodies and certified organic, they’re free from fillers and additives — perfect for those seeking a pure, science-backed boost to mental clarity.

While the earthy flavor might take some getting used to, the high-quality ingredients and easy daily convenience make it a smart choice for daily cognition support.

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Price history for FreshCap Lions Mane on Amazon

Best for Immune Support: New Age

NEW AGE Lions Mane Mushroom Supplement with Turkey Tail Reishi Cordyceps Chaga with Marshmallow Root - 120 Count
Highlights
Multiple mushroom types
Energy boost
Easy to swallow

This all-in-one mushroom powerhouse delivers a big punch with over 20 mushroom extracts, including lion's mane, turkey tail, reishi, and chaga.

The blend is designed to support not just your brain, but your immune system too — making it a versatile addition to your daily routine.

The capsules are easy to swallow, and the energy boost is noticeable without any jitters.

While the mushroom taste is a bit earthy for some, the benefits outweigh the flavor.

Overall, it’s a robust, convenient, and well-rounded supplement for mushroom enthusiasts.

Be sure to also check out the best liquid mineral supplements for more options! Also, here is the price history so you know exactly when to buy!

Price history for New Age on Amazon

Genius Lions Mane

Genius Lion’s Mane Supplement Capsules – Organic Full Spectrum Mushrooms for Cognition, Focus & Memory – 1,200mg Per Serving, 120 Count (60 Servings) – Grown in The USA
Highlights
Enhances focus & clarity
Supports overall wellness
Rich in antioxidants

The Genius Brand’s Lion's Mane capsules are a natural powerhouse for boosting your focus and mental clarity.

With a rich antioxidant profile, it not only supports your brain but also promotes overall wellness.

We love how easy it is to incorporate—just two capsules a day with water before meals.

The high-quality mushroom extract ensures you’re getting the best natural benefits.

Perfect for busy days or deep work sessions, this supplement aligns with any wellness routine.

While the review pool is small, the stellar 4.3-star rating and top rankings speak volumes.

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Price history for Genius Lions Mane on Amazon

NOW Lions Mane

NOW Foods Supplements, Lion's Mane 500 mg, Super Mushroom, Made with Organic Lion's Mane Mushrooms, 60 Veg Capsules
Highlights
Organic fruiting bodies
GMP certified quality
Supports neuronal health

NOW uses organic fruiting bodies, ensuring you're getting the purest form of lion's mane with naturally rich beta-glucans.

Its GMP certification is a stamp of quality, meaning each batch is consistently tested for potency and safety.

We appreciate that it's made in the USA by a family-owned company with over five decades of experience.

While the effects may take a few weeks to kick in, the blend of tradition and science backing this supplement makes it a solid choice for supporting neuronal health.

Plus, if you prefer capsules, they're straightforward — just note they might be a bit large.

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Price history for NOW Lions Mane on Amazon

Real Mushrooms Lions Mane Lion's Mane Brands

Real Mushrooms Lion’s Mane Capsules - Organic Lions Mane Mushroom Extract for Cognitive Function & Immune Support - Brain Mushroom Supplements for Memory and Focus - Vegan, 300 Caps
Highlights
Organic, high-quality ingredients
Supports cognitive function
No jitters or crashes

Real Mushrooms sticks to the essentials with 100% organic Lion's Mane fruiting bodies, ensuring you're getting a pure, potent extract.

The capsules are small and easy to swallow, making daily dosing a breeze.

We love that it contains over 30% beta-glucans—crucial for immune support—and avoids fillers like grains or mycelium.

While the price is a bit higher, the quality craftsmanship and clean ingredients justify the investment.

This supplement is perfect for those seeking a reliable, potent Lion’s Mane to boost cognition and overall vitality.

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Price history for Real Mushrooms Lions Mane on Amazon

Real Mushrooms Lions Mane

Lions Mane Mushroom Cognition Capsules (120 Capsules) Lions Mane Mushroom Powder Extract Capsules | Brain Supplement, Brain Vitamins, Focus Supplement
Highlights
High-quality organic ingredients
Supports cognitive health
Free from starch and grains

Made from 100% organic lion’s mane fruiting bodies, it guarantees a pure, potent extract without any fillers or grains.

The capsules pack a punch with over 30% beta-glucans, verified by third-party labs, naturally boosting your immune system.

Plus, they’re vegan, gluten-free, and non-GMO—perfect for clean eating enthusiasts.

While the capsules might be on the larger side and some users note slow results, the high-quality ingredients and supporting cognitive health make this a reliable choice.

If you're seeking a naturally derived boost, Real Mushrooms is worth considering.

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Price history for Real Mushrooms Lions Mane on Amazon

Double Wood

Lions Mane Supplement Mushroom Capsules (Two Month Supply - 120 Count) Lions Mane Mushroom for Brain Support and Immune Health (Third Party Tested, Grown and Encapsulated in The USA) by Double Wood
Highlights
Supports Brain Growth
Enhances Immune System
No Odor or Taste

Double Wood’s Lion’s Mane is a powerhouse when it comes to supporting neurogenesis and brain cell growth.

It’s carefully sourced, packed with potent ingredients, and comes in a generous two-month supply — perfect for those serious about cognitive health.

The supplement is odorless and tasteless, making it easy to incorporate into your daily routine without any fuss.

Plus, it’s backed by rigorous third-party testing, ensuring purity and quality.

While user feedback is still somewhat limited and long-term benefits are yet to be fully proven, its stellar reviews and focus on immune support make it a top pick for those wanting a clean, reliable option to boost brain function.

Be sure to also check out the best mushroom blends for more options! Also, here is the price history so you know exactly when to buy!

Price history for Double Wood on Amazon

Horbäach Lions Mane Lion's Mane Brands

Horbäach Lions Mane Mushroom Extract | 4200mg | 120 Capsules | Vegetarian, Non-GMO, Gluten Free Supplement
Highlights
High potency (4200mg per serving)
Trusted, quality ingredients
Supports cognitive health

Horbaach’s Lion's Mane offers a staggering 4,200 mg of mushroom extract per serving, making it a powerhouse for cognitive support.

The inclusion of BioPerine ensures your body gets the most out of each dose, maximizing absorption.

Trusted for its quality and tested ingredients, this supplement aligns with those seeking a clean, non-GMO option.

Although it’s flavorless—bland for some—its potency and purity balance that out.

Perfect for anyone wanting a reliable, high-strength supplement backed by reputable manufacturing standards.

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Price history for Horbäach Lions Mane on Amazon

Toniiq Lion’s Mane

Lion’s Mane - Ultra High Potency 10:1 Extract with 30% Polysaccharides - Highly Concentrated & Bioactive - Third-Party Lab Tested - 120 Capsules
Highlights
High polysaccharide content
Pure fruiting bodies
Third-party tested

Toniiq Lions Mane delivers a potent 1800mg of mushroom powder per serving, with a specialized dual-extraction process that maximizes bioavailability of active compounds — a true game-changer.

Made solely from pure fruiting bodies, it boasts a high concentration of polysaccharides that support cognitive function and nerve health.

Each batch undergoes rigorous third-party testing, ensuring purity and potency, which is crucial in today’s supplement market.

While it comes at a slightly higher price and has a mild taste, the quality and efficacy make it a top contender for anyone serious about lion’s mane benefits.

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Price history for Toniiq Lion’s Mane on Amazon

Micro Ingredients Lions Mane Mushroom Powder

Micro Ingredients Organic Lions Mane Mushroom Supplement Powder, 8 Ounce | Natural Superfood for Brain, Energy, & Immune Health | Non-GMO, Vegan
Highlights
Organic, high concentration
Full fruiting body extract
Pure, third-party tested

Micro Ingredients' organic lion’s mane powder is a powerful extract sourced from the whole fruiting body and mycelium, packing 1,500mg per scoop.

The high concentration ensures you're getting a potent dose that may support brain health, immune function, and natural energy levels.

Plus, it's free from common allergens and additives, making it a clean choice.

We appreciate its third-party testing for safety and purity.

While the scoop size might cause some confusion and there's limited reviews, this product’s organic, full-spectrum approach makes it a fantastic option for anyone seeking quality lion’s mane.

Be sure to also check out the best prohormone stack for more options! Also, here is the price history so you know exactly when to buy!

Price history for Micro Ingredients Lions Mane Mushroom Powder on Amazon

OM Mushroom Lion's Mane Brands

OM MUSHROOM SUPERFOOD Lion's Mane Mushroom Capsules Superfood Supplement, 180 Count, 60 Days, Fruit Body and Mycelium Nootropic for Memory Support, Focus, Clarity, Nerve Health, Creativity and Mood
Highlights
Supports memory and focus
Vegan & Non-GMO
Helps nerve health

With a potent 2 grams of organic mushroom nutrition per serving, it delivers a serious boost to memory and focus while promoting a healthy nervous system.

Plus, it ticks all the right boxes for those with dietary preferences — vegan, gluten-free, non-GMO, and vegetarian.

The compact size makes it easy to incorporate into your daily routine.

While some users might find the effects subtle and the price a bit steep, the high-quality ingredients and reliable reviews (4.6 stars from over 500 ratings) make it a solid choice for cognitive support.

Be sure to also check out the best liposomal multivitamin for more options! Also, here is the price history so you know exactly when to buy!

Price history for OM Mushroom on Amazon

Dr Emil Nutrition

DR. EMIL NUTRITION 2100mg Organic Lions Mane Supplement Capsules - Focus, Mental Clarity & Cognition - Nootropic Lion's Mane Mushroom Supplement with Organic Lions Mane
Highlights
Enhances cognitive performance
Pure organic ingredients
Positive user feedback

Dr.

Emil’s Lion’s Mane Smart Shrooms is a powerful brain booster that supports cognitive performance with an organic, high-quality formula.

Each capsule contains 2100 mg of pure, USA-grown Lion’s Mane extract, extracted via a hot water method to maximize nutrients.

Not only does it promote mental clarity and focus, but it also offers immune-boosting benefits, making it a versatile supplement.

Plus, it's non-GMO, gluten-free, and free of unnecessary fillers.

While effects can be gradual and taste may vary, the positive user feedback and premium ingredients make this a top contender for anyone seeking sharp thinking and immune support in one capsule.

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Price history for Dr Emil Nutrition on Amazon

BioSchwartz Mushroom Complex

BioSchwartz Mushroom Complex - Organic Lions Mane Supplement Capsule with Reishi, Turkey Tail, Cordyceps, Shiitake, Chaga, Black Pepper for Max Absorption - Supports Energy, Focus, Memory, 90 Count
Highlights
Enhanced nutrient absorption
Supports mental clarity
High-quality USA-made

The advanced mushroom complex by BioSchwartz packs a powerful punch with a 13-in-1 blend that includes organic lions mane, reishi, chaga, and more, all designed to boost focus, energy, and immunity.

With added BioPerine, absorption is top-notch, meaning you get the most out of every dose.

We especially appreciate its support for mental clarity and cognitive function—perfect for staying sharp.

Made in the USA to high standards, it’s a reliable choice for mushroom enthusiasts.

Just a heads-up: the serving size is a bit hefty, and some may experience mild digestive discomfort.

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Price history for BioSchwartz Mushroom Complex on Amazon

Gaia Herbs Lions Mane Mushroom Lion's Mane Brands

Gaia Herbs, Lions Mane Mushroom, 40 Count
Highlights
Enhances mental clarity
Supports brain health
Reliable, consistent results

Gaia Herbs Lion’s Mane Mushroom offers a potent dose of 2,500mg of organic mushroom extract, making it a solid choice for those aiming to boost mental clarity and overall brain health.

The vegan, gluten-free formula is purity-tested and proudly made in the USA, giving a sense of trustworthy quality.

While some users mention potential libido effects and limited reviews, its reliable, consistent results in supporting focus and cognition make it a standout.

If you're after a natural, straightforward nootropic with a strong reputation, Gaia Herbs is definitely worth considering.

Be sure to also check out the best vegan brain supplements for more options! Also, here is the price history so you know exactly when to buy!

Price history for Gaia Herbs Lions Mane Mushroom on Amazon

TERRA ELMNT Lions Mane

20,000mg 16x Strength Lions Mane Supplement Capsules Super Nootropic w. Ashwagandha & Rhodiola - Highest Potency Lion's Mane Mushroom Extract 50% Polysaccharides Brain Supplements for Memory and Focus
Highlights
High potency extract
Enhances focus & energy
Made in USA GMP

The 16x potency of this Lion's Mane supplement truly sets it apart.

With 1,000mg of highly concentrated extract standardized to 50% Polysaccharides, you're getting an excellent bang for your buck—up to 7 times more Lion's Mane than typical capsules.

Plus, the inclusion of adaptogens like Ashwagandha and Rhodiola means your brain gets a supportive boost for focus, mood, and resilience.

Carefully formulated in the USA and backed by third-party testing, it’s a strong choice for anyone serious about sharpening their mental edge.

Just watch out for possible sleep issues with its potent effects!

Be sure to also check out the best hormone balance gummies for more options! Also, here is the price history so you know exactly when to buy!

Price history for TERRA ELMNT Lions Mane on Amazon

Herbify Lions Mane

HERBIFY Lions Mane Supplement - Daily Mushroom Supplement for Memory, Focus & Clarity - Brain Booster - Lions Mane Tincture for Immune Support - 4 Fl oz
Highlights
Enhances focus and memory
High-quality, USA-made
Liquid form more effective

Herbify’s Lions Mane Mushroom Extract is a powerhouse for boosting mental clarity and focus.

The liquid form makes it more bioavailable, so you feel the benefits faster.

Plus, made with high-quality American ingredients, it’s a trusted choice for those who care about purity and safety.

We love the easy-to-use dropper and its ability to support immune health and nerve regeneration — a true multitasker in your wellness routine.

While it has a few limited reviews, the stellar 4.4-star rating speaks volumes about its effectiveness.

Overall, a top-notch lions mane option!

Be sure to also check out the best hormone balance tea for more options! Also, here is the price history so you know exactly when to buy!

Price history for Herbify Lions Mane on Amazon

Nootropics Depot Lions Mane Lion's Mane Brands

Nootropics Depot Lions Mane Mushroom Capsules | 8:1 Whole Fruiting Body Dual Extract | 500mg | 60 Count | Hericium erinaceus
Highlights
Boosts cognitive function
Lab tested and verified
Traditional mushroom benefits

… The Nammex Lion's Mane Mushroom, made from traditionally sourced fruiting bodies, delivers on its cognitive promises with a pure, potent formula.

Its lab-tested verification guarantees top-notch quality, which is a huge plus for those seeking reliable supplements.

This mushroom not only supports brain health but also aids digestion thanks to beta-glucans, making it a well-rounded addition to your daily routine.

While there’s a slight chance of mild confusion or libido effects in some users, the overall benefits for mental clarity and traditional efficacy make it a standout choice.

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Price history for Nootropics Depot Lions Mane on Amazon

VitaRaw Lion’s Mane

Organic Lions Mane Supplement Capsules 2400 mg - Powerful Nootropic - Helps Maintain Memory, Energy, and Mental Clarity - Vegan Brain Booster Focus Pills - Real Lion's Mane Supplement - Melena de Leon
Highlights
Full-spectrum nutrients
Higher beta-glucans
Made from fruiting bodies

Our organic lion’s mane supplement is packed with full-spectrum nutrients derived from real fruiting bodies, ensuring you're getting the authentic mushroom benefits.

The hot water extraction process preserves a healthy range of beta-glucans, boosting brain health more effectively than dual-extraction methods.

With 2390mg of organic lion’s mane per serving, plus black pepper for better absorption, it hits the sweet spot for cognitive support.

While the capsules are on the larger side and you need four daily, the high-quality ingredients and rigorous testing make this a standout choice for anyone serious about mental clarity and neuro support.

Be sure to also check out the best ashwagandha tea for more options! Also, here is the price history so you know exactly when to buy!

Price history for VitaRaw Lion’s Mane on Amazon

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