14 Top Omega-3 Vitamin D and K Supplements to Boost Your Wellness

Discover the best omega-3 vitamin D and K supplement to boost your health with top picks, quick reviews, and expert insights in one concise guide.
BrandMy RatingPrice
Primemd
Best Value Option
9.0/10
Viva Naturals
Best for Heart Health
9.4/10
Oceanblue
Best for Bone Support
9.0/10
Nusava
Best for Immune Boost
8.8/10
Oceanblue
7.8/10

Best Omega-3 Vitamin D and K Supplement

Looking to supercharge your health with a powerhouse trio? Discover the ultimate blend of Omega-3, Vitamin D, and Vitamin K—a dynamic combination that fuels your body’s defenses and sharpens your mind in the most efficient way. Dive in to find the best supplements that deliver convenience, clarity, and real results in just a few streamlined choices.

Best Value Option: PrimeMD Fish Oil

5-in-1 Fish Oil Omega 3 Fatty Supplements (2100mg) - Omega 3 Fish Oil with Vitamins D3 K2 and CoQ10 - Lemon Flavored (120 softgels)
Highlights
Rich in EPA/DHA
No fishy aftertaste
Contains CoQ10, D3, K2

Our team chose this as the "Best Value Option" because it combines high-quality ingredients in a comprehensive 5-in-1 formula that covers all your essential nutrients—EPA, DHA, D3, K2, and CoQ10—at an unbeatable price.

The easy-to-swallow softgels boast a refreshing lemon flavor that masks the fishy aftertaste, making daily intake much more pleasant.

Designed for optimal heart, brain, and immune support, these softgels work in harmony to promote mobility and cellular energy.

For anyone seeking a cost-effective, all-in-one wellness boost, this product is a clear winner.

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Price history for PrimeMD Fish Oil on Amazon

Best for Heart Health: Viva Naturals Omega 3

Omega 3 Fish Oil Supplement for Women and Men - 2500 mg Triple Strength Fish Oil Pills with Re-Esterified Omega 3 Fatty Acids including EPA, DHA DPA - 180 Pescatarian-Friendly Softgels
Highlights
Triple strength formula
Pure, high-quality fish oil
No fishy aftertaste

With 2,500 mg of triple-strength fish oil per serving, it packs a powerful punch for your heart and brain health.

The omega-3s—EPA, DHA, and DPA—are delivered in re-esterified triglyceride form, which means your body absorbs them more efficiently, maximizing benefits.

Plus, it’s purified to reduce mercury and other contaminants, giving you peace of mind with every capsule.

Made from wild-caught, sustainably sourced fish, it boasts quality and purity certifications like IFOS and Labdoor.

While the price has edged up and capsules are softgels (instead of gummies), this supplement truly delivers on its promise of high potency and purity.

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Price history for Viva Naturals Omega 3 on Amazon

Best for Bone Support: Oceanblue Omega-3 2100

Oceanblue Professional Omega-3 2100 with Vitamin D3 – 60 ct – Triple Strength Burpless Fish Oil Supplement with High-Potency EPA, DHA, DPA and Vitamin D3 – Wild-Caught – Vanilla Flavor (30 Servings)
Highlights
Good omega-3 ratio
No fishy aftertaste
Sustainable sourcing

OceanBlue Omega-3 2100 with Vitamin D3 earns our "Best for Bone Support" badge because it pairs potent EPA and DHA with high-dose Vitamin D3 and K2, all in one easy-to-take softgel.

The vanilla flavor makes it a pleasure to swallow—no fishy aftertaste or reflux here!

Plus, it's sustainably sourced and free from heavy metals and artificial ingredients, so you can feel good about what you're taking.

While the large size might be a bit daunting for some, the benefits for bone health, calcium absorption, and overall well-being make it a top pick in our shortlist.

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Price history for Oceanblue Omega-3 2100 on Amazon

Best for Immune Boost: NUSAVA Vitamin D3 K2 Drops

(2 Pack) Organic Vitamin D3 K2 Drops with MCT Oil Omega 3, Maximum Strength Vitamin D Liquid 5000 IU, No Fillers, Non-GMO Liquid D3 for Faster Absorption and Immune Support (Pineapple, 2 Fl Oz)
Highlights
High potency formula
Fast absorption liquid
Organic & Non-GMO

Its high-potency formula combines 125 mcg of Vitamin D3, 120 mcg of Vitamin K, and 250 mg of Omega-3, delivering a powerful punch in every drop.

The liquid form means faster absorption compared to capsules, helping your body get what it needs quickly.

Plus, with organic, non-GMO ingredients and a delightful pineapple flavor, it makes supplementation almost enjoyable.

While the oily texture and bitter taste might be a tiny hurdle, the benefits for immune support, bones, and heart health make it a top contender for those seeking a 4-in-1 powerhouse supplement.

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Price history for NUSAVA Vitamin D3 K2 Drops on Amazon

Oceanblue Omega-3 2100

Oceanblue Professional Omega-3 2100 with Vitamin K2 and Vitamin D3-60 Count - Triple Strength Burpless Fish Oil Omega-3 Supplement with EPA, DHA & DPA - Wild Caught - Orange Flavor, 30 Servings
Highlights
No fishy aftertaste
Supports heart and bones
Sustainably sourced

The 3-in-1 formula truly simplifies your routine, combining omega-3s with vitamins D3 and K2 in one easy capsule.

The orange flavor makes swallowing a breeze—no fishy aftertaste or reflux to bother you.

Plus, it's sustainably sourced from pristine waters, giving you peace of mind about your environmental impact.

While the large capsule size might be a squeeze for some, the support for heart, bones, and immunity makes it worth it.

Overall, a potent, clean, and convenient choice for comprehensive wellness.

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Price history for Oceanblue Omega-3 2100 on Amazon

Carlson

Carlson - Elite Omega-3 Plus D & K, 700 mg Omega-3s + D3 & K2, Function, Bone Health & Immune Support, Lemon, 60+30 Softgel
Highlights
High absorption of D
Includes Omega-3s
Quality and purity

Carlson Labs combines a robust 700 mg of omega-3s, including EPA and DHA, with a potent dose of 2,000 IU vitamin D3 and 90 mcg of vitamin K2 as MK-7, creating a powerhouse supplement for bone and overall health.

We love its commitment to freshness, potency, and purity, ensuring you're getting a top-tier product.

While it might have a fishy aftertaste and is only available online, its high absorption rate and proven quality make it a great choice for those looking to support their health efficiently.

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Price history for Carlson on Amazon

Signify Nature Omega 3 Omega-3 Vitamin D and K Supplement

SIGNIFY NATURE Omega 3 Fish Oil Supplement with Vitamin D3 5000 IU - 1000mg Triglyceride Capsules for Brain Health - Omega3 EPA DHA + VIT D 3-90CT
Highlights
High absorption formula
Pure, toxin-free
Supports immunity & bones

Signify Nature's Omega 3 + Vitamin D3 offers a powerful blend of EPA and DHA alongside a hefty 5000 IU of Vitamin D3, making it an ideal all-year-round supplement.

The molecular distillation process guarantees a superior purity free from toxins like mercury and PCBs, ensuring optimal absorption in every capsule.

We appreciate the high-quality, third-party tested formula that supports both heart and bone health while boosting immunity.

Yes, the capsules are on the larger side, but that’s a small trade-off for the pure, toxin-free benefits.

Perfect for those who want effective, pharmaceutical-grade supplementation in one simple softgel.

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Price history for Signify Nature Omega 3 on Amazon

Nature Made Vit D3 K2

Nature Made Vitamin D3 K2, 5000 IU (125 mcg) Vitamin D, Dietary Supplement for Bone, Teeth, Muscle and Immune Health Support, 30 Softgels, 30 Day Supply
Highlights
Easy to swallow capsules
Supports bone health
No aftertaste

The Nature Made Vitamin D3 K2 Softgels deliver a potent 5000 IU of Vitamin D paired with 100 mcg of K2, supporting your bones and cardiovascular health effectively.

The softgels are easy to swallow and free of any overbearing aftertaste, making daily dosing a breeze.

Plus, made in the USA with high-quality ingredients, they align with trusted standards.

While the bottle offers only 30 capsules—meaning a quick reorder is needed—it’s perfect for those with higher supplement needs or looking to optimize bone and artery health with minimal fuss.

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Price history for Nature Made Vit D3 K2 on Amazon

Life Extension Vitamins D & K

Life Extension Vitamins D and K with Sea-Iodine, vitamin D3, vitamin K1 and K2, iodine, supports immune, bone, arterial and thyroid health, non-GMO, gluten-free, 60 capsules
Highlights
High-quality ingredients
Supports immune health
Small, easy capsules

Life Extension's Omega-3 with Vitamin D and K delivers a potent blend designed to support overall health.

The high-quality ingredients ensure maximum potency, while the inclusion of multiple vitamin K forms optimizes calcium absorption for stronger bones.

Plus, the added iodine helps keep your thyroid happy and functioning properly.

The small capsules are a breeze to swallow, making daily supplementation simple.

Although the price is on the higher side, the purity, scientifically-backed doses, and USA-made quality make this a top-tier choice for those serious about their health.

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Price history for Life Extension Vitamins D & K on Amazon

Nutritional Roots Omega-3 Vitamin D and K Supplement

Plant Based Vitamin D3 K2, Vitamin D3 5000 iu, Vitamin D3 and Probiotics, Algal Omega 3 DHA, Organic Food Blend, Doctor's Choice, Vegan, 1 Monthly Supply, 30 ct
Highlights
Vegan-friendly ingredients
Includes K2 and Omega-3
Third-party tested

Nutritional Roots’ Plant-Based Vitamin D3 K2 has garnered the Delicious Living Magazine Consumer Choice Gold Award for a reason.

Formulated by a medical professional, it combines a robust 5000 IU of Vitamin D with K2, Omega-3 DHA from algae, and probiotics—all in one vegan-friendly capsule.

While it may have a strong taste that some find off-putting, the quality and thoughtful ingredient pairing make it a standout choice.

Plus, the third-party testing ensures transparency and safety.

If you’re looking for a vibrant, energized supplement that supports bone health and gut wellness, this could be your perfect match.

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Price history for Nutritional Roots on Amazon

NOW Ultra Omega 3-D

NOW Supplements, Ultra Omega 3-D™, Omega-3 Fish Oil + Vitamin D-3, Cardiovascular Support*, 90 Softgels
Highlights
High EPA & DHA
Molecularly distilled
Supports heart health

Now Ultra Omega 3-D offers a potent dose of omega-3s with 600 mg EPA and 300 mg DHA per softgel, plus a boost of 1,000 IU Vitamin D-3 to support overall health.

The molecular distillation process ensures purity, free from contaminants like mercury and PCBs—crucial for peace of mind.

While the softgels are sizable and might lead to some fishy burps, the high-quality formula makes it a top pick for cardiovascular support.

If you're seeking a robust supplement trusted by many, this one deserves a serious look.

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Price history for NOW Ultra Omega 3-D on Amazon

Metagenics Vitamin D3 K

Metagenics Vitamin D3 + K - for Immune Support, Bone Health & Heart Health* - Vitamin D with MK-7 (Vitamin K2) - Non-GMO - Gluten-Free - 60 Softgels - 10,000 IU
Highlights
Clinically Proven Formula
Easy to Swallow
Supports Bone & Immunity

Metagenics D3 10,000+ K delivers a clinically proven formula that’s designed to support both your bones and immune health with ease.

The high-potency vitamin D3 (10,000 IU) combined with a bioavailable form of vitamin K2 makes it a powerful duo for maintaining optimal calcium balance.

Plus, it's easy to swallow — no hassle at all.

While it’s on the pricier side, its trustworthy brand reputation and 4.7-star rating make it worth considering for those serious about their supplement game.

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Price history for Metagenics Vitamin D3 K on Amazon

Now Vitamin D-3 & K-2 Omega-3 Vitamin D and K Supplement

NOW Supplements, Vitamin D-3 & K-2, 1,000 IU/45 mcg,Plus Cardiovascular Support*, Supports Bone Health*, 120 veg Capsules
Highlights
Supports bone health
Cardiovascular support
Easy to swallow

The NOW Vitamin D-3 & K-2 veggie capsules pack a powerful punch for supporting bone health and cardiovascular wellness.

With an easy-to-swallow capsule, it makes daily supplementation a breeze.

The blend combines 1,000 IU of Vitamin D-3 with 45 mcg of K-2, both backed by extensive research.

Plus, it's non-GMO, kosher, and soy-free, ensuring quality and accessibility.

While some users may find the dosage limited or haven't seen noticeable benefits yet, the product’s GMP certification and long-standing family-owned reputation give us confidence in its consistency and purity.

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Price history for Now Vitamin D-3 & K-2 on Amazon

Bronson Vitamin K2 D3

Bronson Vitamin K2 (MK7) with D3 Supplement Non-GMO Formula 5000 IU Vitamin D3 & 90 mcg K2 MK-7 Easy to Swallow D & K Complex, 120 Capsules
Highlights
Enhances calcium absorption
Laboratory tested quality
Combines K2 & D3

Bronson's K2&D3 capsules deliver a powerful combo that our bodies love.

The pairing optimizes calcium utilization, strengthening bones and promoting overall health.

The capsules are laboratory-tested, ensuring high quality, and naturally free of gluten and soy — a plus for sensitive stomachs.

While the size might take some getting used to and flavor options are limited, the effectiveness and purity more than make up for it.

If you're looking for a trusted, USA-made supplement that truly delivers, this one is a solid choice.

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Price history for Bronson Vitamin K2 D3 on Amazon

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