16 Top Vitamin B12 Supplements for Dogs

Discover the best vitamin B12 supplement for dogs with our quick, colorful guide to boost your pup’s health and vitality effortlessly.
BrandMy RatingPrice
Ka'dee Simply Beyouful
Best Cheap Pick
8.2/10
Nutramax Laboratories
Best for Large Breeds
9.6/10
Wonder Laboratories
Best for EPI Recovery
9.4/10
Nutrition Strength
Best for Long-Term Use
7.8/10
Nutramax Laboratories
9.4/10

Best Vitamin B12 Supplement for Dogs

Looking to boost your dog’s vitality with the perfect Vitamin B12 supplement? Navigating the sea of options can be overwhelming, but fear not—here’s your quick guide to the best B12 supplements for dogs, delivered in a crisp, colorful snapshot of top picks to keep tails wagging and energy soaring.

Best Cheap Pick: Ka'Dee Simply Beyouful

Liquid Vitamin B-12 Complex Drops for Dogs and Cats - Nutritionally Balanced Vet Formulated - Energy, Appetite, Mood - Recovery - Helps Cognition and Brain, Joints, Skin, Digestion
Highlights
Easy to administer
Promotes healthy coat
Long-lasting supply

As our "Best Cheap Pick," it offers fantastic value with a potent 2 fl oz bottle that lasts, making daily supplementation simple and cost-effective.

The liquid form is super easy to give—just a few drops mixed into food or water, reducing stress for both pet and owner.

We love that it’s suitable for both cats and dogs, ensuring versatility.

Plus, its formulation promotes a healthy, shiny coat and overall wellness.

While the soil smell might be a small downside, its affordability and convenience make it a top choice for budget-conscious pet parents.

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Price history for Ka'Dee Simply Beyouful on Amazon

Best for Large Breeds: Nutramax Cobalequin

Nutramax Laboratories Cobalequin B12 Supplement for Medium to Large Dogs, 45 Chewable Tablets, Hydrolyzed Chicken, 2.08 ounces
Highlights
Easy to administer
Vet recommended
Supports energy levels

Designed specifically for medium to large dogs, Nutramax Cobalequin is a veterinarian-recommended supplement that genuinely caters to bigger breeds' B12 needs.

The chewable tablets are super easy to serve — you can crush them or give them whole, making daily administration hassle-free.

Plus, it may reduce the need for B12 injections, which is a big plus for pet owners looking for a more convenient option.

Backed by over 30 years of Nutramax’s trusted legacy, this supplement combines science and safety, supporting your dog’s energy levels and overall wellness.

Overall, it’s a solid choice for larger pups needing a boost!

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Price history for Nutramax Cobalequin on Amazon

Best for EPI Recovery: Wonder Laboratories Pet Factor B-12

Pet Factor B-12 | Vitamin B-12 in Methylcobalamin Form | Popular in Treatment of EPI in Dogs 180 Capsules
Highlights
Recommended by Epi4Dogs
Enhances B-12 Absorption
Made in the USA

Pet Factor Vitamin B12 by Wonder Laboratories is our top pick for EPI recovery.

Recommended by the Epi4Dogs Foundation, it contains methylcobalamin B-12, which is designed for optimal absorption, especially important for dogs recovering from Exocrine Pancreatic Insufficiency.

The formulation also includes Folic Acid and Intrinsic Factor, boosting nutrient utilization.

Made in the USA in an FDA-registered facility, it ensures quality and safety.

While some might find the capsule size a bit bulky, the 180 capsules pack great value for all-stage, all-breed pups needing a B-12 boost.

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Price history for Wonder Laboratories Pet Factor B-12 on Amazon

Best for Long-Term Use: Nutrition Strength B Complex

Vitamin B for Dogs, Complete B Complex for Dogs, Promote Blood Cell & Nervous System Health, Help Sustain Cellular Energy Production & Maintain Brain Function, 120 Chewable Tablets
Highlights
Supports Brain and Nervous System
Manufactured in USA
Supports Cellular Energy Production

Designed with long-term health in mind, this complete B complex supplement offers consistent support for blood cell production and nervous system health—perfect for daily supplementation.

The high-quality formulation ensures your pup’s cellular energy stays boosted, helping them stay lively and alert.

Plus, the added benefits for cardiovascular and gluco-regulatory functions are a plus, especially for aging or sensitive dogs.

Manufactured in the USA with human-grade ingredients, it meets strict standards for safety and efficacy.

While some dogs may dislike the flavor, the overall quality and ongoing support make it a top pick for long-term use.

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Price history for Nutrition Strength B Complex on Amazon

Cobalequin

Nutramax Cobalequin B12 Supplement for Cats and Small Dogs, 45 Count (Pack of 1)
Highlights
Easy to serve
Vet recommended
Supports overall wellness

Nutramax's Cobalequin offers a convenient oral solution for small dogs and cats, making B12 supplementation a breeze without the need for injections.

The tablets are easy to serve—crushable or whole—adapting to your pet’s preferences.

As a veterinarian-recommended brand with over 30 years of experience, Nutramax ensures quality and safety with science-backed ingredients.

While the taste might fade over time, its support for overall wellness and simplicity makes it a great choice for pet owners who want effective B12 support without hassle.

Be sure to also check out the best liquid joint supplement for dogs for more options! Also, here is the price history so you know exactly when to buy!

Price history for Cobalequin on Amazon

WONDER PAWS

B12 Supplement for Dogs – Vitamin B-12 for Dogs of All Ages, Sizes & Breeds – Vitamin B12 for Dogs as Superior Methylcobalamin, Cobalamin & Folate (5-MTHF) – 90 Beef Flavored Chewables
Highlights
Highly absorbable B12 forms
Tasty beef flavor
Supports multiple health areas

Wonder Paws combines two powerful forms of vitamin B12, cobalamin and methylcobalamin, for superior absorption—a game-changer for supporting your pup’s immune, brain, and nerve health.

Plus, the addition of metabolically active folate (5-MTHF) provides a comprehensive boost to their metabolism and blood cell formation.

The beef-flavored chewables are highly palatable, making giving daily doses a breeze for dogs of all sizes.

While the dosage may vary and requires consistent administration, the quality and care put into this supplement make it a fantastic choice for optimizing your dog’s well-being.

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Price history for WONDER PAWS on Amazon

Rx Vitamins B12 Vitamin B12 Supplement for Dogs

Rx Vitamins Rx B12 for Dogs & Cats - Vitamin B12 Liquid Supplement for Pets - Dog Vitamins for Small & Large Breed - Cat Health Supplies - 4 oz.
Highlights
Supports energy & vitality
Easy to administer
Suitable for all sizes

Rx Vitamins' B12 supplement delivers a powerful punch in a convenient liquid form that’s perfect for any breed size.

The easy-to-measure dropper makes administering a seamless experience—even for the most finicky pets.

This vitamin supports vital functions like energy, immune health, and cell growth, making it a comprehensive choice for pets who need a boost.

Plus, formulated by vets, it guarantees safety and high-quality ingredients.

While regular dosing is a must and taste can vary, overall, this supplement offers a reliable way to keep your furry friend feeling vibrant and healthy.

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Price history for Rx Vitamins B12 on Amazon

Wonder Laboratories Pet Factor B-12

Pet Factor B-12 | Vitamin B-12 in Methylcobalamin Form | Popular in Treatment of EPI in Dogs. 90 Count
Highlights
Popular treatment for EPI
Made in the USA
Enhanced absorption

As a popular treatment for EPI in pets, Wonder Laboratories’ B-12 supplement is a solid choice, especially since it's recommended by the Epi4Dogs Foundation.

It naturally boosts your dog’s absorption and utilization of B-12, thanks to its formulation with methylcobalamin, folic acid, and intrinsic factor.

Plus, it's made in the USA in an FDA-registered facility, giving peace of mind.

While it may offer limited impact for larger dogs and doesn't include added flavor, its high rating and proven effectiveness make it a reliable option for pet owners seeking quality B-12 support.

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Price history for Wonder Laboratories Pet Factor B-12 on Amazon

Nutrition Strength B12 for Dogs

Vitamin B12 for Dogs Plus Folate & Calcium, Support the Nervous System & Blood Cell Formation, Help Sustain Cellular Energy Generation & Maintain DNA Synthesis, 120 Chewable Tablets
Highlights
Supports blood cell formation
Made with methylcobalamin
High customer satisfaction

Nutrition Strength's vitamin B12 supplement for dogs stands out with its high-quality methylcobalamin, the biologically active form of B12 that supports red blood cell production and overall vitality.

The formula also includes folic acid and calcium, which work together to promote cognitive health and cardiovascular function.

Plus, it’s made in the USA, adhering to strict manufacturing standards, so you know you're giving your pup a safe, premium supplement.

The 365-day guarantee shows their confidence in the product, making it a tried-and-true choice for supporting your furry friend's well-being.

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Price history for Nutrition Strength B12 for Dogs on Amazon

iVitamins Vitamin B12 Supplement for Dogs

Vitamin B for Dogs | Vitamin B Complex for Dogs | Vitamin B12 for Dogs | Dog Vitamins | B12 Vitamins for Dogs | Vitamin B Dog Supplements | B Complex for Dogs | B12 for Dogs | Do1 fl oz: Bacon Flavor
Highlights
Delicious bacon flavor
Supports overall health
Quick absorption for all breeds

The delicious bacon flavor makes administration a breeze, even for picky eaters.

The liquid formula ensures quick absorption, supporting your dog's overall health—brain function, cellular health, and energy levels—across all breeds and sizes.

Plus, it's made in the USA with high-quality ingredients, giving pet owners peace of mind.

While some may not see dramatic effects immediately, the gentle support it provides is noteworthy.

Overall, this supplement offers a comprehensive, tasty, and convenient way to keep your furry friend feeling their best.

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Price history for iVitamins on Amazon

Infinite Health Labs

Liquid Vitamin B-12 for Dogs and Cats - Vet Formulated - Effective for All Animals Methylcobalamin (Methyl B12) - Energy, Appetite and Mood - Made in USA
Highlights
Supports nervous system health
Improves energy levels
Made in the USA

The Infinite Health Labs Liquid Vitamin B-12 is a bioactive form of the vitamin that easily absorbs, offering noticeable support for your dog's nervous system and energy levels.

Perfect for pups with EPI or those needing a little extra immune boost, it’s convenient to add right to their food or water.

While it might not do much for increasing appetite, its USA-made quality and veterinarian-backed formulation give us confidence in its effectiveness.

Plus, the 100% satisfaction guarantee means you can try it worry-free.

Ultimately, a solid choice for maintaining your furry friend’s health!

Be sure to also check out the best supplement for dog incontinence for more options! Also, here is the price history so you know exactly when to buy!

Price history for Infinite Health Labs on Amazon

Rx Vitamins

Rx Vitamins Amino B Plex for Pets - B Vitamin Complex Plus Amino Acids for Dogs & Cats - Vitamin Supplements for Dogs' & Cats' Total Body Support - 2 oz.
Highlights
Palatable and easy to dose
Supports pet energy
Suitable for picky eaters

The Rx Vitamins Amino B Plex is a highly palatable liquid that even the pickiest pups will gladly accept—no fuss needed.

It’s packed with essential B vitamins and spirulina, offering a natural boost of energy and vitality, especially beneficial for senior or active outdoor dogs.

The dosing is straightforward, with adjustable amounts based on your dog’s weight, making it convenient to customize.

While some pets may be sensitive to the flavor or smell, the overall effectiveness and ease of use make this a great choice for supporting your pet's health and energy levels daily.

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Price history for Rx Vitamins on Amazon

PetLab Co Multivitamin Chews Vitamin B12 Supplement for Dogs

PetLab Co. 22 in 1 Dog Multivitamin - Support Dog's Immune Response, Skin, Coat, Joints & Overall Health - Vitamins A, E, D, B12, Minerals, Antioxidants - Chewable Pork Flavor
Highlights
Dog loves the taste
Supports skin & coat
Contains 22 vitamins

PetLab Co.'s Dog Multivitamin Chews are a tasty and convenient way to bolster your pup’s health.

They contain a robust 22-vitamin formula, supporting everything from a shiny coat to a strong immune system.

Plus, dogs seem to really love the delicious pork flavor, making daily supplementation a breeze.

Made in the USA with high-quality ingredients, these treats are perfect for all life stages.

While the flavor might not be everyone’s favorite and the dosage instructions could be clearer, the overall benefits and dog-approved taste make these chews a solid choice for proactive pet owners.

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Price history for PetLab Co Multivitamin Chews on Amazon

Nutrition Strength Iron for Dogs

Iron for Dogs with Anemia to Support Blood Health, Blood Cell Formation & Oxygen Supply, Iron Supplement for Anemic Dogs + Vitamin C, Folate, Vitamin B12, 120 Chewable Tablets
Highlights
Supports blood health
Promotes red blood cell
Made in the USA

Nutrition Strength's Iron for Dogs tablets are a highly-rated supplement that supports blood health and red blood cell formation—crucial for energetic, healthy pets.

Packed with vitamin C, B12, and folate, it helps prevent anemia by boosting oxygen transport and cellular energy.

The convenient pack of 120 tablets makes daily supplementation easy, and the 365-day guarantee shows how confident the brand is in its quality.

Although some dogs might refuse pills, the benefits of bolstering blood health and supporting overall vitality make this an excellent choice—especially since it’s made right here in the USA.

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Price history for Nutrition Strength Iron for Dogs on Amazon

Golden Paw Multivitamin

Liquid Multivitamin for Dogs | 10-in-1 Multivitamin for Cats | Vitamin B Complex for Cats & Dogs | Cranberry Supplement | for Urination, Digestion, Breathing & Movement | for All Pets Ages | 2 Oz
Highlights
Natural ingredients
Easy dropper application
Supports overall health

This multi-vitamins liquid is packed with 10 essential nutrients that support everything from your pet's skin and eyes to their joints and digestive health.

The inclusion of natural cranberry extract adds a bonus of urinary health benefits, making it a great all-in-one supplement.

Its easy dropper application makes dosing hassle-free, especially for different breeds and ages.

Plus, it’s made with love, using natural ingredients that prioritize your pet’s well-being.

While the short shelf life and occasional soft stools are minor quirks, overall, this supplement proves to be a practical, health-boosting choice for your furry friends.

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Price history for Golden Paw Multivitamin on Amazon

LAORICI Iron Supplement Vitamin B12 Supplement for Dogs

Iron Supplement for Cats & Dogs - Liquid Iron with Vitamin C and B12, Improves Anaemia, Low Energy & Lethargy in Pets, Promotes Blood Health, Red Blood Cell Formation, Enhances Vitality
Highlights
Fast absorption
Natural ingredients
Easy to administer

The liquid iron supplement boasts fast absorption thanks to its polysaccharide complex, ensuring your furry friend gets quick relief from anemia symptoms.

Its natural ingredients make it gentle on sensitive stomachs, and the easy drop form means no more struggles during medicating time.

Plus, it seamlessly mixes into food or water, making administration a breeze.

While it’s a fantastic option to boost energy and vitality, keep in mind that the B12 dosage isn’t specified, and the limited reviews mean more feedback is needed.

Still, a solid choice for supporting your pup’s health!

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Price history for LAORICI Iron Supplement on Amazon

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