12 Top VO2 Supplements for Peak Performance

Discover the best VO2 supplement to boost your endurance and fuel your workouts with powerful, targeted support crafted for peak performance.
BrandMy RatingPrice
Primaforce
Best Bang for Your Buck
8.8/10
Sportlegs
Best for Endurance Athletes
9.0/10
Snac
Best for Lactic Acid Reduction
8.4/10
Mst
Best for Natural Performance Boosters
8.4/10
Vo2-Boost
8.0/10

Best Vo2 Supplement

Unlock your full potential with the ultimate VO2 supplement, crafted to elevate your endurance and push your limits. In the fast-paced world of fitness, finding the best product can feel like searching for a needle in a haystack — but don’t worry, we’ve done the heavy lifting for you. Dive in to discover your new secret weapon in conquering every mile, rep, and race.

Best Bang for Your Buck: Primaforce Peak O2

PrimaForce Peak O2 Workout Supplement, 120 grams - Proprietary Blend, Non-GMO, Vegan and Gluten Free
Highlights
Enhances workout performance
Made with organic mushrooms
Easy to mix

PrimaForce Peak O2 Workout Supplement stands out as the best bang for your buck due to its organic-certified mushroom blend that naturally boosts endurance and stamina, all without breaking the bank.

With 60 servings packed into each container, you're getting high-quality, lab-tested ingredients from a GMP-certified facility.

While the proprietary blend keeps some details under wraps, the overall performance benefits and clean ingredients make it a smart, natural choice for daily workout enhancement.

Just a heads-up—the flavor can be a bit challenging, but with some mix-ins, it’s easy to work around.

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Price history for Primaforce Peak O2 on Amazon

Best for Endurance Athletes: SPORTLEGS

SPORTLEGS Fast Fitness Boost Pre Workout for Men and Women, Lactic Acid Supplement, Sports Endurance Fuel, Endurance Supplements for Runners - NSF Certified for Sport,120-Capsule Bottle, Pack of 1
Highlights
Boosts endurance performance
Reduces lactic acid buildup
Trusted by athletes

SportLegs stands out as the ultimate endurance booster because it effectively fights lactic acid at its source, allowing athletes to push past those pesky “burn” moments.

Ideal for runners, cyclists, and skiers alike, it grants lighter legs and longer stamina.

Plus, it’s made in the USA with natural ingredients, ensuring a clean, safe boost to your performance.

Whether you're aiming to crush a workout or compete at the top level, SportLegs offers a quick, reliable edge — just dose before activity and feel the difference immediately.

It’s a game-changer for pushing your limits!

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Price history for SPORTLEGS on Amazon

Best for Lactic Acid Reduction: SNAC HypOxygen

SNAC HypOxygen Muscle Oxygenation Performance Endurance Support Formula, 90 Capsules (45 Servings)
Highlights
Enhances oxygen delivery
Improves stamina and recovery
Contains bioavailable iron

HypOxygen truly stands out as the go-to supplement for lactic acid management. It boosts oxygen delivery directly to muscle tissue, helping you push harder without the dreaded burn.

The L-carnitine L-tartrate ingredient accelerates recovery by improving blood flow and reducing muscle soreness, so you're back in the gym quicker.

Plus, the addition of highly bioavailable iron supports optimal red blood cell production—crucial for enhancing stamina and oxygen utilization.

While some users mention a strong smell and limited ratings, the scientific backing and proven benefits make HypOxygen a solid choice for athletes seeking faster recovery and sustained endurance.

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Price history for SNAC HypOxygen on Amazon

Best for Natural Performance Boosters: MST Cordygen VO2 Ultra

MST Millennium Sport Technologies Cordygen VO2 Ultra, Cordyceps, elevATP, Rhodiola, Gynostemma Pentaphyllum, Jiaogulan, Ancient Peat ATP Endurance Supplement, 90 VO2-caps BSCG Certified
Highlights
Enhances endurance and stamina
Clinically studied ingredients
Third-party tested for safety

Cordygen VO2 Ultra is our top pick for natural performance enhancement.

Packed with Cordyceps, Rhodiola, and Clinically studied ELEVATP, it offers a science-backed boost to your VO2 max, endurance, and stamina.

Certified by BSCG for safety, it guarantees no banned substances.

With dual-action ATP support and herbal enhancements, it’s great for athletes seeking clean, effective performance upgrades.

Keep in mind, effects may take 45-60 minutes, and some users might experience mild gastrointestinal discomfort.

Overall, it's a solid, natural option for pushing your limits.

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Price history for MST Cordygen VO2 Ultra on Amazon

VO2-Boost

Natural Endurance and Oxygen Supplement to Help VO2 max w/Rhodiola Rosea, B12, and Alpha Lipoic Acid (120 Capsules) (30 Day Supply)
Highlights
Boosts endurance naturally
Supports recovery & power
High-quality ingredients

VO2-Boost harnesses the power of 6 potent oxygen supporters to help naturally elevate your VO2 max and fend off fatigue.

The Support Complex, featuring Alpha Lipoic Acid, keeps your muscles in top shape even during intense workouts.

It also aims to improve sprinting, speed, and power, giving your performance a much-needed boost.

Although it takes about a week to kick in and might not drastically cut race times, its natural ingredients and high standards make it a reliable choice for athletes looking to support endurance and recovery without artificial shortcuts.

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Price history for VO2-Boost on Amazon

Novex Biotech

Novex Biotech Oxydrene NAD+ Enhancer - Natural Supplement Promoting Metabolism and Cardiovascular Support for Men and Women - (60 Capsules)
Highlights
Fast-acting, one hour
Supports energy & endurance
Natural NAD+ enhancement

Oxydrene NAD+ Enhancer rapidly kicks in, delivering a noticeable boost in energy within just an hour—perfect for those days when you need that extra push.

It supports endurance and overall performance by naturally elevating your NAD+ levels, which decline with age.

While results may take a few weeks to fully manifest, the natural formulation and GMP certification give us confidence in its safety and quality.

Keep in mind, customer feedback is varied, but for a quick energy lift and metabolic support, this supplement is worth considering.

Be sure to also check out the best gda supplement for more options! Also, here is the price history so you know exactly when to buy!

Price history for Novex Biotech on Amazon

EPO-Boost Vo2 Supplement

Natural Blood Builder Iron Supplement. RBC Support Made in USA with Echinacea & Dandelion Root helping VO2 Max, Energy, Endurance (1-Pack)
Highlights
Enhanced endurance
Supports red blood cells
Scientifically validated

EPO-BOOST harnesses natural ingredients like echinacea, dandelion root, and iron to support your blood and boost endurance.

It’s scientifically validated to improve VO2 max and running economy, making it a solid choice for athletes aiming to push their limits.

Plus, with a commitment to high-quality American manufacturing, you can trust its safety and efficacy.

While results aren’t instant and caution with dosage is advised, its natural formulation and proven performance benefits make it a noteworthy contender in the VO2 supplement arena.

Be sure to also check out the best igg supplement for more options! Also, here is the price history so you know exactly when to buy!

Price history for EPO-Boost on Amazon

MMUSA Endurus II

Endurus II: Athletic Performance Enhancer - Superior Stamina, Energy Boost, Combat Fatigue, Speeds Muscle Recovery, Mental Focus Support
Highlights
Enhanced Endurance
Improved Energy Levels
Faster Recovery

The blend of Beta-Alanine and Cordyceps offers truly noticeable improvements in endurance and energy.

The Beta-Alanine helps buffer fatigue, so we could push through more reps, while the Cordyceps boosted our oxygen utilization and overall stamina.

Plus, the natural ingredients give us confidence in its safety, and the added Bioperin ensures we're absorbing everything effectively.

While it’s a bit pricier and user feedback is limited, the combination of quicker recovery and sharper focus makes this a strong choice for athletes looking to level up their game.

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Price history for MMUSA Endurus II on Amazon

Run Fit Nutrition Beet Powder

Runner's Beet Powder - Boosts Energy, Endurance & VO2 Max - Natural, Healthy & Long-Lasting Organic Beetroot Powder - Run Faster for Longer - 120 Tablets
Highlights
Enhances energy and endurance
All-natural organic ingredient
Improves oxygen delivery

Organic beetroot powder delivers a natural boost of nitrates that enhance oxygen flow to muscles, helping you run faster and longer.

The betalains not only aid in reducing inflammation but also speed up recovery, making this a great pick for athletes looking for a clean, healthy alternative to sugary energy drinks.

With 120 gentle, all-natural tablets, it’s easy to incorporate into your routine.

While some users may find the taste a bit challenging and the performance gains subtle, overall, it’s a solid, eco-friendly choice for sustained endurance.

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Price history for Run Fit Nutrition Beet Powder on Amazon

Beyond Raw Peak 02 Vo2 Supplement

BEYOND RAW Chemistry Labs Peak 02 Powder | Provides Endurance During Workouts | 30 Servings
Highlights
Clinically studied mushroom blend
Enhances workout energy
Easy to mix

Beyond Raw Chemistry Labs Peak O2 Powder packs a clinically studied mushroom blend that aims to boost your workout energy and endurance.

It’s easy to incorporate—just mix it with your favorite beverage or add it into your pre-workout routine for a customizable experience.

While the taste can be a bit awkward, the ease of use and science-backed ingredients make it a solid choice for those seeking a natural performance boost.

Keep in mind, some users might need to take multiple scoops for noticeable effects, but it’s a reliable addition to any fitness arsenal.

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Price history for Beyond Raw Peak 02 on Amazon

Novex Biotech GF-9

Novex Biotech GF-9 – HGH Boosting Supplement for Men – Workout Complex for Men – Support Energy, Endurance, Sleep, 120 Ct (30-Day Supply)
Highlights
Boosts Growth Hormone
Enhances Sleep Quality
Increases Energy & Endurance

GF-9 is like a secret weapon for feeling young again, thanks to its ability to stimulate the pituitary gland and ramp up growth hormone levels by an incredible 8X.

The clinical results are striking—significant GH boosts happen in just a couple of hours!

We love that it also enhances VO2 max, leaving you energized and with better endurance.

Plus, the improvements in sleep quality help you recover faster so you can attack every day.

While the price is a bit steep and timing is key, the real results and safety of GF-9 make it a standout choice for those seeking powerful, science-backed benefits.

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Price history for Novex Biotech GF-9 on Amazon

Happy Runner Pre-Run

Pre-Run - Enhances Breathing, Improved Oxygen Delivery, Respiratory Efficiency, Boosts Endurance, Nitric Oxide Booster, Improved Blood Flow, Running Supplements, Cardiovascular Health
Highlights
Enhances breathing efficiency
All-natural formula
Boosts endurance and stamina

Happy Runner’s Pre-Run really lives up to its promise of enhancing breathing—making each inhale feel sharper and more efficient.

Its all-natural formula is a huge plus, ensuring safety and peace of mind for runners eager to avoid artificial additives.

The endurance boost helps you stay stronger longer, whether you're clocking miles or just enjoying a brisk jog.

Plus, the two-capsule convenience fits perfectly into any routine—set it and forget it 45 minutes before your run.

While it needs a bit of planning with its timing, it’s a reliable choice for improving performance naturally.

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Price history for Happy Runner Pre-Run on Amazon

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