16 Endurance Supplements for Runners You Need to Try

Discover the best endurance supplements for runners to boost stamina and crush your races with quick, effective picks for peak performance.
BrandMy RatingPrice
Tailwind Nutrition
Most Cost-Effective
9.0/10
Sportlegs
Best for Lactic Acid Management
9.0/10
Happy Runner
Best for Long-Distance Performance
10.0/10
Happy Runner
Best for Long-Distance Performance
10.0/10
Peregrune
8.8/10

Best Endurance Supplements for Runners

Ready to unlock your runner’s potential with top-tier endurance supplements? Whether you're chasing a personal record or simply aiming to keep pace mile after mile, discovering the right boost can transform your performance. Dive into our curated list of the best endurance enhancers for runners and power through with confidence and vigor.

Most Cost-Effective: Tailwind Nutrition

Tailwind Nutrition Endurance Fuel, Electrolyte & Hydration Sports Drink Mix Powder, Gluten-Free, Vegan, Mandarin, 50 Servings
Highlights
Great taste and hydration
Prevents stomach issues
Keeps energy steady

As the most cost-effective option, it offers a whopping 50 servings per container, making it perfect for long-distance runners and budget-conscious athletes alike.

The balanced blend of electrolytes, calories, and hydration simplifies your training, letting you ditch multiple supplements.

Its light, pleasant flavors—ranging from Berry to Lemon—are easy on the palate and won’t leave a weird aftertaste, plus it dissolves quickly and cleanly.

Best of all, it avoids gut issues thanks to its clean ingredients and natural sugars, so you can focus on your run without stomach troubles.

All in all, a reliable, tasty choice that keeps your endurance up without breaking the bank.

Be sure to also check out the best mineral supplement for water for more options! Also, here is the price history so you know exactly when to buy!

Price history for Tailwind Nutrition on Amazon

Best for Lactic Acid Management: Sportlegs

SPORTLEGS Fast Fitness Boost Pre Workout for Men and Women, Lactic Acid Supplement, Sports Endurance Fuel, Endurance Supplements for Runners - NSF Certified for Sport,120-Capsule Bottle, Pack of 1
Highlights
Reduces lactic acid buildup
Boosts endurance and performance
Trusted by athletes

SportLegs stands out as the Best for Lactic Acid Management because it’s specifically formulated to tackle that stubborn build-up that slows runners down.

It targets lactic acid at its source, allowing you to push past the 'burn' and reach new performance heights.

Whether you're gearing up for a marathon or squeezing in a long run, this supplement helps you maintain lighter legs and run longer without fatigue.

Plus, being NSF Certified for Sport and made in the USA reassures us it's a clean, trusted choice for serious athletes.

Be sure to also check out the best allergy supplements for dogs for more options! Also, here is the price history so you know exactly when to buy!

Price history for Sportlegs on Amazon

Best for Long-Distance Performance: Happy Runner Pre-Run

Pre-Run - Enhances Breathing, Improved Oxygen Delivery, Respiratory Efficiency, Boosts Endurance, Nitric Oxide Booster, Improved Blood Flow, Running Supplements, Cardiovascular Health
Highlights
Improves Breathing Efficiency
Supports Endurance & Stamina
All-Natural, Safe Formula

Happy Runner’s Pre-Run is our top pick for "Best for Long-Distance Performance" because it truly enhances respiratory efficiency, making each breath smoother and more natural.

It supports sustained stamina, so you can keep pushing without hitting a wall.

Plus, its all-natural formula means you’re fueling your body safely and effectively — no artificial fillers here.

Just two capsules about 45 minutes before your run, and you’re set for improved breathing and endurance at every mile.

It’s a simple, reliable addition to your routine that helps you perform at your best, mile after mile.

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Price history for Happy Runner Pre-Run on Amazon

PEREGRUNE

Runner Multivitamin – Engineered Vitamin with Antioxidants for Health/Running Recovery – Complete B Complex for Endurance, Energy – Probiotics, Whole Foods – Certified Running Supplements
Highlights
Enhanced Energy Boost
Contains Antioxidants
Whole Foods Ingredients

PERGRUNE offers a robust dose of Vitamin B complex that keeps your energy levels high from start to finish, thanks to the added B4, B8, and B10 for complete support.

It also packs powerful antioxidants like Vitamins C and E, helping your body fight off inflammation and recover faster after those tough runs.

Plus, with Vitamins A and D, it ensures you’re prepared for early mornings or late-night thrashes, especially indoors.

Made from whole foods and crafted in the USA, it’s a trustworthy choice—just be mindful of the larger pill size and potential overuse with other supplements.

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Price history for PEREGRUNE on Amazon

Clif Bloks

CLIF BLOKS - Energy Chews - Variety Pack - Non-GMO - Plant Based - Fast Fuel for Cycling and Running - Quick Carbohydrates and Electrolytes - 2.12 oz. Packets (12 Count)
Highlights
Excellent for long workouts
Great flavor variety
Easy to digest

CLIF Bloks deliver quick, convenient energy with a soft, easy-to-eat texture that won't slow you down mid-run.

The variety of flavors keeps things tasty and fresh, even on those long-distance days.

Made with plant-based, non-GMO ingredients, they align with health-conscious choices without sacrificing performance.

While the size is slightly large and they can get a bit sticky, their high-carb content and customizable sodium levels make them a top contender for fueling endurance.

Overall, they’re a solid choice for athletes seeking reliable, flavorful energy in a portable package.

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Price history for Clif Bloks on Amazon

BPN G.1.M Endurance Supplements for Runners

BARE PERFORMANCE NUTRITION, BPN G.1.M Go One More Sport, Endurance Training Fuel, Superior Carbohydrate & Electrolytes Powder Formula, Reduce Fatigue, Fruit Punch, 25 Servings
Highlights
Quick-digesting carbs
Supports endurance training
No jitteriness

The BPN G.1.

M SPORT delivers fast-digesting carbs, thanks to Cluster Dextrin, which provides a steady energy release without those annoying sugar crashes.

Plus, its electrolyte blend keeps you hydrated and helps reduce muscle cramps during long runs.

While it can sometimes form clumps or leave a starchy film, these minor inconveniences are worth the performance boost.

The Fruit Punch flavor is refreshingly flavorful, though it can vary slightly between batches.

Best of all, every batch is third-party tested for banned substances, so you can fuel confidently.

For runners seeking reliable endurance support, this one's a solid pick.

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Price history for BPN G.1.M on Amazon

GU Energy Roctane

GU Energy Roctane Ultra Endurance Electrolyte Capsules,Informed Choice, Energy for Before, During or After Any Workout, 50-Count Bottle
Highlights
Enhances hydration, electrolytes
Contains Vitamin D benefits
Soothes gastrointestinal distress

GU Energy Roctane Ultra Electrolyte Capsules are a game changer for any runner needing reliable hydration support.

They deliver a potent blend of sodium, magnesium, and chloride to keep water balanced and plasma volume steady during intense sessions.

Plus, the added Vitamin D helps support bone health, which is crucial for long-term endurance.

We also appreciate the inclusion of ginger root to calm any gastrointestinal upset that sometimes accompanies rigorous activity.

While the flavor options are a bit limited, these capsules are compact, easy to take on the go, and deliver consistent performance—perfect for those demanding workouts or races.

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Price history for GU Energy Roctane on Amazon

Peregrune Runner

Runner Multivitamin & Joint Support Supplement – Antioxidants, Vitamin B Complex, Probiotics for Health, Energy, Endurance, Recovery - Glucosamine Chondroitin, MSM – GMP Running Supplements
Highlights
Contains comprehensive B-vitamins
High antioxidant levels
Supports joint & knee health

The comprehensive blend of B-vitamins truly supports energy production, helping runners push through longer sessions with ease.

The addition of powerful antioxidants like Vitamins C and E means your body gets extra protection against the oxidative stress caused by intense activity.

Plus, the tri-joint complex with Glucosamine, Chondroitin, and MSM keeps those knees feeling smooth and ready for the next run.

We also appreciate the 3X MSM boost—a real game-changer for joint stiffness.

Made in the USA and GMP certified, it’s a trustworthy choice for high-quality supplementation.

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Price history for Peregrune Runner on Amazon

Huma Chia Energy Gel Endurance Supplements for Runners

Huma Chia Energy Gel, Variety 12 Pack - Stomach Friendly, Real Food Energy Gels for Endurance Exercise
Highlights
Natural ingredients
Great taste variety
Steady energy boost

Huma Gel stands out with its all-natural ingredients, giving you a clean energy boost without artificial junk.

The delicious fruit flavors make it enjoyable to consume mid-race, turning a chore into a treat.

Thanks to the fine chia seeds, energy delivery is smooth and consistent, helping you maintain stamina without crashes.

Plus, its digestibility means fewer stomach issues, a huge plus for long-distance runners.

The limited caffeine options might be a downside for some, but the variety of flavors and steady performance make up for it.

Overall, a natural, tasty, reliable choice for endurance athletes.

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Price history for Huma Chia Energy Gel on Amazon

Snap Supplements Nitric Oxide Booster

Snap Supplements Nitric Oxide Booster Supplement with L Arginine and L Citrulline Essential Amino Acids and Ginseng Root, Energy, Heart Health, Muscle Growth & Circulation Support, 60 Capsules
Highlights
Enhances stamina and energy
Supports healthy circulation
No stimulants or sugars

The Nitric Oxide Booster from Snap Supplements naturally promotes healthy circulation and supports your body's oxygen delivery, making it an excellent choice for runners.

It boosts stamina without relying on stimulants or sugars, so you can focus on your performance without jitters or crashes.

Plus, its focus on vein and vessel health means you're not just running longer—you’re also taking care of your cardiovascular health.

While effects may vary from person to person and it’s not a magic fix, its clean, USA-manufactured formula makes it a strong contender in the endurance supplement game.

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Price history for Snap Supplements Nitric Oxide Booster on Amazon

SaltStick

SaltStick Electrolyte FastChews - Mixed Berry Chewable Electrolyte Tablets - Salt Tablets for Runners, Electrolyte Chews for Hydration - 60 Count
Highlights
Fast absorption
Convenient chewable format
Contains essential electrolytes

SaltStick FastChews deliver almost instant electrolyte replenishment, making them perfect for those long, sweaty runs.

The bite-sized chewables are incredibly convenient—no mixing or mess—and dissolve quickly so you can get back to your stride in no time.

Packed with essential minerals like sodium, potassium, calcium, and magnesium, they help keep cramps at bay and hydration levels optimal.

Although slightly pricier and with a limited electrolyte dose, their clean ingredients and USA-made quality make them a top pick for dedicated runners.

Perfect for a quick boost on the go!

Be sure to also check out the best supplements for spider veins for more options! Also, here is the price history so you know exactly when to buy!

Price history for SaltStick on Amazon

BSN Amino X Endurance Supplements for Runners

BSN Amino X Muscle Recovery & Endurance Powder with BCAAs, Intra Workout Support, 10 Grams of Amino Acids, Keto Friendly, Caffeine Free, Flavor: Fruit Punch, 30 servings (Packaging May Vary)
Highlights
Supports muscle recovery
Easy to mix
Sugar and caffeine free

Packed with 10g of micronized amino acids per serving, it’s a game-changer for muscle recovery after those long runs.

The inclusion of BCAAs helps you push through those tough training sessions, boosting muscle endurance without any sugar or caffeine to weigh you down.

Plus, it mixes easily—no clumps here—making it perfect for a quick boost on the go.

While it does contain Red 40 and offers limited flavor options, its performance benefits and clean formula make it a solid choice for dedicated runners looking to elevate their endurance game.

Be sure to also check out the best supplement for methylation for more options! Also, here is the price history so you know exactly when to buy!

Price history for BSN Amino X on Amazon

SaltStick

SaltStick Electrolyte Capsules with Vitamin D | Salt Pills with Electrolytes for Running, Endurance Sports Nutrition, Running Supplements | 100 Count Electrolyte Pills
Highlights
Fast absorption
Reduces heat stress
Easy to swallow

SaltStick electrolyte capsules stand out with their fast absorption and scientific formulation that helps reduce heat stress and leg cramps.

They're super easy to swallow, making them perfect for quick hydration on the go.

Whether you're hitting the trails, cycling, or just pushing through a tough workout, these capsules provide a reliable electrolyte boost without any added fillers or sugars.

The clean ingredients appeal to health-conscious athletes, and their versatility makes them suitable for any activity where hydration matters.

Just keep in mind, they may require frequent dosing and offer limited flavor options, but overall, they’re a solid choice for endurance runners seeking quick electrolyte support.

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Price history for SaltStick on Amazon

Honey Stinger

Honey Stinger Organic Honey Waffle, Energy Stroopwafel for Exercise, Endurance and Performance, Sports Nutrition for Home & Gym, Pre & During Workout, Box of 16 Waffles, 16.96 Ounce (Pack of 16)
Highlights
Delicious honey flavor
Portable and mess-free
Organic ingredients

The Honey Waffle offers a delicious honey-infused flavor that keeps us craving more, making it an enjoyable pre- or mid-workout snack.

Its portable, mess-free design means we can toss it in our gym bag without any fuss.

Crafted with organic ingredients, it matches our commitment to clean fueling.

While the flavor could be a bit sweeter and the serving size small, this waffle packs a punch with 19g of quick-absorbing carbs and electrolytes to support endurance.

Overall, it’s a compact, tasty, and performance-ready option for runners on the go.

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Price history for Honey Stinger on Amazon

Skratch Labs Endurance Supplements for Runners

Skratch Labs Hydration Powder | Sport Drink Mix | Electrolytes Powder for Exercise, Endurance, and Performance | Lemon + Lime | 20 Servings | Non-GMO, Vegan, Kosher
Highlights
Real fruit flavor
Fast hydration
No artificial ingredients

Skratch Labs' Lemon & Lime endurance drink stands out with its real fruit flavor and clean ingredient list, appealing to health-conscious athletes.

It hydrates quickly, thanks to a smart electrolyte mix that closely mimics what you lose in sweat, helping you stay energized during intense runs.

The light, refreshing taste is a plus, especially since it contains no artificial colors or preservatives.

While the flavor may be mild for some and it comes with a higher price tag, its commitment to quality and transparent ingredients make it a top contender for those who prioritize natural, effective hydration.

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Price history for Skratch Labs on Amazon

PEREGRUNE

Runner Joint Support Supplement - Healthy Knees, Back, Cartilage, & Joints – Glucosamine Chondroitin MSM- GMP Certified Running Supplements and Joint Support for Athletes – 90 Capsules
Highlights
Supports joint health
Increased mobility
Clinically formulated

Peregrune's Tri-Joint Complex is specifically formulated for active runners, with a potent blend of Glucosamine, Chondroitin, and triple MSM to lubricate and support joint health.

The higher MSM dosage is a real game-changer for reducing stiffness, helping you move more freely and comfortably mile after mile.

While the capsules might be a bit on the larger side and the price is higher, the clinically backed ingredients offer a promising boost to your joint longevity.

For those serious about running pain-free, this supplement delivers where it counts—supporting sustained mobility and active running.

Be sure to also check out the best catalase supplements for more options! Also, here is the price history so you know exactly when to buy!

Price history for PEREGRUNE on Amazon

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