18 Equol Supplements You Should Know About

Discover the best equol supplement to boost your wellness journey with our quick, clear guide to top picks and vibrant options for radiant health.
BrandMy RatingPrice
Now Foods
Best Bang for Your Buck
9.0/10
Garden of Life
Best for Menopause Relief
9.0/10
Garden of Life
Best for Menopause Relief
9.0/10
Smnutrition
Best for Hormonal Balance
8.6/10
Equelle
7.6/10

Best Equol Supplement

Looking to unlock the secret benefits of equol without sifting through endless options? Discover the best equol supplements designed to boost your wellness journey with precision and ease. Dive into our curated guide and find your perfect match in just moments.

Best Bang for Your Buck: Now Isoflavones

NOW Foods Supplements, Soy Isoflavones, 60 mg (Plant Compounds Particularly Concentrated in Soybeans, like Genistein, Daidzein and Glycitein), 120 Veg Capsules
Highlights
Effective menopause relief
High genistein levels
Vegan and non-GMO

As our "Best Bang for Your Buck" pick, it offers a high concentration of soy isoflavones that truly stands out.

Thanks to a unique extraction process, the genistein content is notably higher than most competitors, providing effective support for menopause and hormone balance.

Plus, it checks all the boxes with certifications like vegan, non-GMO, and allergen-free, making it suitable for many dietary needs.

While individual results can vary and some may experience soy-related side effects, its outstanding value and quality make it a fantastic pick for those seeking reliable menopause relief without breaking the bank.

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Price history for Now Isoflavones on Amazon

Best for Menopause Relief: Garden of Life

Garden of Life Herbals Menopause Supplement with S-equol & Trans-Resveratrol for Multi-Symptom Relief, Keranat for Thicker, Fuller Hair Growth – Non-GMO, Gluten-Free, Vegan, Berry Flavor, 30 Servings
Highlights
Supports hair growth
Clinically proven ingredients
Vegan and natural

Garden of Life Herbals Menopause + Hair Growth truly lives up to its reputation as the "Best for Menopause Relief".

The clinically proven S-equol tackles those pesky hot flashes, night sweats, and sleep disturbances head-on, making it a reliable go-to.

Plus, the addition of Trans-Resveratrol supports overall muscle and sleep quality.

We love how it also promotes hair health, thanks to the powerful Keranat extract.

With its vegan, non-GMO formula and delightful berry aroma, this softgel makes managing menopause feel a little more enjoyable and a lot more natural.

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Price history for Garden of Life on Amazon

Best for Hormonal Balance: SMNutrition DIM

DIM Supplement 200 mg | Estrogen Balance for Women & Men | Hormonal Acne, Hormone Balance, Menopause & Antioxidant Support | Clean Label Project Certified, Vegan & Soy Free Diindolylmethane | 60 Ct.
Highlights
Supports hormone balance
Improves skin health
Certified quality

DIM 200 by Smoky Mountain Naturals truly earns its spot as the best for hormonal balance.

It packs a punch with diindolylmethane, supporting estrogen regulation for women and men alike.

Women find relief from bloating, PMS, and menopausal symptoms, while men benefit from boosted prostate health and energy levels.

Plus, it works deep at the cellular level to promote glowing skin from within—no superficial fixes needed.

The supplement’s commitment to quality is evident with numerous certifications, making it a reliable choice.

Just keep in mind, individual results can vary, and some might experience mild side effects.

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Price history for SMNutrition DIM on Amazon

EQUELLE

EQUELLE Menopause Supplement for Women to Support Hot Flashes, Sleep*, Muscle Aches & More - Multi-Symptom Relief - Premium Dietary Supplement - 60 Tablets
Highlights
Reduces hot flashes
Easy to swallow
Backed by 20+ years science

Equelle's blend of 10 mg S-equol is a game-changer for menopause relief, mimicking estrogen's effects naturally.

The easy-to-swallow tablets make daily support a breeze, and many users report a noticeable reduction in hot flashes and better sleep.

Backed by over 20 years of science, Equelle offers a trustworthy solution grounded in research.

While it isn't perfect—some users mentioned digestion hiccups and limited reviews—its promise of hormone support in a safe, plant-based form makes it a compelling choice for many women navigating menopause.

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Price history for EQUELLE on Amazon

Fair Kanpai Equol

;Equol Pure Isoflavones 42mg Equol Domestic Manufacture 30 Tablets for 60 Days Supplement Soy Isoflavones Beauty with Plastic Box
Highlights
High customer rating
Compact package size
Trusted manufacturer

Otsuka's equol supplement boasts a high customer rating and comes in a compact, travel-friendly package, making it super convenient to keep on hand.

The trusted manufacturer behind it adds to its credibility, giving us confidence in its quality.

However, some users report no noticeable effects yet, and with limited review feedback, it's a bit of a mystery whether long-term benefits are just around the corner.

Despite that, its top-tier ratings and reputable backing make it a solid choice for those curious about equol's benefits.

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Price history for Fair Kanpai Equol on Amazon

Nature's Sunshine Equolibrium Equol Supplement

Nature's Sunshine Equolibrium, 60 Capsules
Highlights
Contains powerful Equol antioxidant
Improves sleep quality
No side effects

Equolibrium stands out with its inclusion of Equol, a potent antioxidant that offers multi-dimensional prostate support.

Unlike typical supplements, it directly binds to DHT, helping to prevent enlargement and related issues from the inside out.

Many users report not just prostate benefits but improved sleep quality, thanks to reduced nighttime urination.

Best of all, it works without causing unwanted side effects, making it a safe choice.

While it may be pricier and lacks full ingredient transparency, its unique DHT-binding power and antioxidant benefits make it a solid pick for those seeking targeted prostate health in a straightforward, twice-daily capsule.

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Price history for Nature's Sunshine Equolibrium on Amazon

EQUELLE

EQUELLE Test Menopause Supplement for Women to Support Hot Flashes, Sleep*, Muscle Aches & More - Multi-Symptom Relief - Premium Dietary Supplement - 60 Tablets (2 Pack)
Highlights
Supports menopause symptoms
Plant-based S-equol content
Easy-to-swallow tablets

Equelle offers a plant-based S-equol that aims to mimic estrogen, providing support for hot flashes and sleep quality — common menopause challenges.

The easy-to-swallow tablets make daily dosing simple, and with over 20 years of research backing it, safety and efficacy are well-grounded.

However, responses vary; some users see quick relief, while others notice slower results.

It's also worth noting that a few might experience allergies or mixed effectiveness.

Overall, Equelle is a thoughtful, science-backed option for those seeking targeted menopause support, with room for individual results.

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Price history for EQUELLE on Amazon

Otsuka Equelle

Otsuka EQUELLE for Womens Health & Beauty Pouch Type 120 Tablets with Plastic Box
Highlights
Effective hot flash reduction
Improves mood swings
Japanese formulation quality

Ekuoreru offers a high-quality Japanese formulation that’s crafted through a fermentation process using food-grade soybeans and lactic acid bacteria—no fillers here!

Many users have reported notable relief from hot flashes and improved mood swings, making it a promising choice for those seeking hormonal balance.

However, the price tag is on the steeper side, and since the packaging is in Japanese, it might be a bit confusing for non-native speakers.

Plus, the uncertain side effects mean it’s best to start slowly and monitor your response.

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Price history for Otsuka Equelle on Amazon

Nutrum Estrolife Equol Supplement

Estrolife Anti-Aging Support for Women by Nutrum, Vegan Supplement for Long Lasting Female Hormonal Balance, Ovarian Function, Skin Hydration, Elasticity and Firmness, Menopause Relief, 60 Capsules
Highlights
Effective menopause relief
High-quality, USA made
Enhances skin hydration

Estrolife offers effective menopause relief with a high-quality, USA-made formulation that’s crafted by seasoned clinicians.

It’s designed to seamlessly support hormonal balance, reducing hot flashes, night sweats, and mood swings—delivering real comfort during perimenopause and menopause.

Plus, the added bonus of enhanced skin hydration makes it a dual-purpose gem.

While it’s a bit on the pricier side and has limited reviews, its potent botanical blend and third-party testing give us confidence in its safety and efficacy.

A trusted choice for women seeking natural support.

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Price history for Nutrum Estrolife on Amazon

Estroven

Estroven Complete Multi-Symptom Menopause Supplement for Women, 28 Ct., Clinically Proven Ingredient Provide Menopause Relief & Night Sweats & Hot Flash Relief, Drug-Free & Non-GMO
Highlights
Effective hot flash relief
Clinically tested ingredients
Natural menopause support

Its clinically-tested ingredients deliver powerful relief from hot flashes, with some users experiencing up to a 90% reduction.

The natural rhubarb extract works gently to support overall menopause comfort, and it’s free from hormones, soy, gluten, and GMOs — making it a safe choice for many.

Of course, patience is key; results typically take 30-45 days, but the all-in-one formula helps improve sleep, energy, and stress levels during those weeks.

With consistent daily use, this supplement offers a reliable and natural approach to easing menopause symptoms.

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Price history for Estroven on Amazon

21st Century Soy Isoflavones

21st Century Soy Isoflavones Veg Capsules, 60Count
Highlights
Vegetarian formula
Supports heart and bones
Effective for mood boost

The vegetarian soy formula is a smart choice for women looking to support heart, bone health, and mood—plus, it’s easy on the stomach.

With over 730 reviews and an average of 4.4 stars, it clearly resonates with users.

While there’s some concern over varying doses and limited long-term data, the benefits, like mood enhancement and overall support, make it a solid option for those seeking plant-based help.

Just keep in mind, as with any supplement, side effects are possible, so proceed with awareness.

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Price history for 21st Century Soy Isoflavones on Amazon

Life Extension Estrogen Equol Supplement

Life Extension Estrogen for Women, Helps Relieve hot Flashes and Night Sweats, Soy isoflavones, Norway Spruce Extract, chasteberry, Hormone-Free, Gluten Free, Non-GMO, Vegetarian, 30 Tablet
Highlights
Relieves hot flashes
Supports women’s health
Hormone-free formula

The Norway spruce extract works wonders for easing those pesky hot flashes and night sweats, making it a reliable go-to during menopause.

Plus, the blend of standardized soy isoflavones, broccoli, licorice, chasteberry, and dong quai offers a comprehensive approach to supporting overall women’s health without relying on hormones.

Keep in mind, some users might experience an upset stomach, and the larger pill size can be a bit challenging.

Still, with premium ingredients and a hormone-free formula, it’s a solid option for natural relief and health support.

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Price history for Life Extension Estrogen on Amazon

Qunol CoQ10

Qunol CoQ10 100mg Softgels, Ultra CoQ10 100mg, 3x Better Absorption, Antioxidant for Heart Health & Energy Production, Coenzyme Q10 Vitamins and Supplements, 4 Month Supply, 120 Count
Highlights
3X better absorption
Cardiologist recommended
Water and fat soluble

Qunol Ultra stands out with 3X better absorption than standard CoQ10, meaning your body gets more of what it needs quicker.

It's cardiologist recommended, giving added confidence in its quality and efficacy.

Its water and fat-soluble formula ensures optimal bioavailability, which regular CoQ10 struggles with.

Plus, it plays a key role in energy production—crucial as CoQ10 levels naturally decline with age or medication use.

While it’s on the pricier side and can be sensitive to heat, the potential benefits make it a strong choice for those serious about supporting their heart and energy levels.

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Price history for Qunol CoQ10 on Amazon

Puritan's Pride Soy Isoflavones

Puritan's Pride Non-GMO Soy Isoflavones 750mg, Dietary Supplement with Active Daidzein, Genistein, and Glycitein Supports Menopause and Hot Flashes, 120 Rapid Release Capsules
Highlights
Noticed quick effects
Effective for menopause symptoms
Improves mood and energy

With quick effects, many users report noticeable relief from menopause symptoms like hot flashes and mood swings.

It also seems to give a nice boost in energy, making daily life a bit easier.

The star rating of 4.4 from a handful of reviews suggests it's a trusted choice by those who’ve tried it.

While the review data is limited, the overall effectiveness and fast results make this a solid pick for women seeking natural support.

However, keep in mind the potential hormonal effects and the current availability status when considering this supplement.

Be sure to also check out the best andro supplements for more options! Also, here is the price history so you know exactly when to buy!

Price history for Puritan's Pride Soy Isoflavones on Amazon

Carlyle Equol Supplement

Carlyle Soy Isoflavones for Women and Men 1500mg | 200 Capsules | Non-GMO, Gluten Free Extract Supplement
Highlights
Natural estrogen source
High dosage (1,500 mg)
Trusted quality standards

Carlyle's Equol supplement packs a punch with a potent 1,500 mg of soy isoflavones per serving, making it a solid choice for those seeking natural estrogen support.

The high dosage ensures you get a significant boost, all while adhering to trusted quality standards and being free of common allergens.

The capsules are a bit large, but that’s a small trade-off for the clean ingredients and guaranteed quality Carlyle promises.

Overall, it’s a reliable, plant-based option to enhance your wellness journey with confidence.

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Price history for Carlyle on Amazon

Natures Craft

Complete Herbal Menopause Supplement for Women - Female Hormone Balance Capsules for Night Sweats, Hot Flashes & Mood Swings with Dong Quai, Chaste Berry & Black Cohosh Root - 60 Count Pack
Highlights
Effective hot flash relief
Relaxes and promotes sleep
Natural herbal ingredients

Natures Craft’s menopause support supplement combines carefully chosen herbal ingredients like black cohosh, red clover, and chaste tree berry to target those pesky hot flashes and night sweats effectively.

Plus, it’s designed to balance hormonal shifts and promote restful sleep, making it a true all-in-one solution.

While some users report heartburn and occasional irritability, the overall benefits — especially relief from hot flashes — make this a worthwhile option for women seeking natural support during menopause.

A blend that’s both thoughtful and effective!

Be sure to also check out the best t2 supplement for more options! Also, here is the price history so you know exactly when to buy!

Price history for Natures Craft on Amazon

Centrum

Centrum Complete Multivitamin Supplement + Hot Flash Support Menopause Support Tablets, with Clinically Studied geniVida, 30 Count
Highlights
Effective hot flash relief
Easy to swallow
Non-GMO & hormone-free

Centrum's Hot Flash Support is a comprehensive multivitamin designed specifically for women navigating menopause.

Powered by clinically studied geniVida, it effectively reduces the frequency and duration of hot flashes, with results often visible after 12 weeks of daily use.

Plus, it’s packed with 19 essential nutrients like B-vitamins for brain health and calcium, vitamin D, and magnesium for strong bones.

The best part?

It’s non-GMO, hormone-free, and suitable for vegetarians, making it a convenient and trustworthy choice for women seeking relief with peace of mind.

Be sure to also check out the best dmg supplement for more options! Also, here is the price history so you know exactly when to buy!

Price history for Centrum on Amazon

Life Extension Estrogen Balance Elite Equol Supplement

Life Extension Estrogen Balance Elite, Menopause Support Supplement, Hormone Balance, hot Flashes, Night Sweats, Vaginal Dryness, Gluten-Free, Non-GMO, Vegetarian, 60 Tablets
Highlights
Supports hormonal balance
Relieves menopause symptoms
Plant-based ingredients

Its plant-based formulation is designed to help keep your hormones in harmony, easing common menopause discomforts like hot flashes and night sweats.

The blend of fenugreek, red clover, chaste tree, and black cohosh works synergistically to support healthy estrogen and progesterone levels, making it a solid choice for women seeking natural relief.

Plus, with ingredients sourced for quality and purity, you can trust it's made with care.

That said, a mild taste and some variability in results mean it’s not perfect for everyone, but overall, a reliable and thoughtful option.

Be sure to also check out the best dlpa supplement for more options! Also, here is the price history so you know exactly when to buy!

Price history for Life Extension Estrogen Balance Elite on Amazon

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