16 Glutathione Supplements for Melasma Revealed

Discover the best glutathione for melasma and brighten your skin with our quick, expert-reviewed picks. Your glow-up starts here.
BrandMy RatingPrice
Now Foods
Best Low-Cost Alternative
9.2/10
Northern Crown Cosmetics
Best for Skin Brightening
7.8/10
Codeage
Best for Anti-Aging
8.8/10
Glocalcare
Best for Hyperpigmentation
8.0/10
Vaite
7.6/10

Best Glutathione for Melasma

Struggling with melasma can feel like a battle against stubborn skin discoloration that refuses to fade. Enter glutathione, a radiant skin booster celebrated for its brightening properties and antioxidant power. Discover the best glutathione options that can help unveil a more luminous, even-toned complexion.

Best Low-Cost Alternative: NOW Glutathione

NOW Foods Supplements, Glutathione 500 mg, With Milk Thistle Extract & Alpha Lipoic Acid, Free Radical Neutralizer*, 60 Veg Capsules
Highlights
Easy to swallow capsules
Noticed brighter skin
Boosts energy levels

Now Foods offers a straightforward, budget-friendly option with their Glutathione capsules.

The easy-to-swallow capsules make daily routine a breeze, and many users have reported brighter, more radiant skin after consistent use.

While it doesn’t specifically target melasma, its antioxidant properties may help support skin health overall.

Keep in mind, the limited reviews mean results can vary, and long-term effects still need more clarity.

Still, at such an affordable price point, this product is a smart choice for those starting their pigmentation journey without breaking the bank.

Be sure to also check out the best glutathione for mold detox for more options! Also, here is the price history so you know exactly when to buy!

Price history for NOW Glutathione on Amazon

Best for Skin Brightening: Northern Crown Cosmetics Glutathione Pills

Glutathione Whitening Pills - 120 Capsules 2000mg Glutathione - Effective Skin Lightening Supplement - Dark Spots, Melasma & Acne Scar Remover, Hyperpigmentation Treatment - Anti-Aging Antioxidant
Highlights
Effective Skin Brightening
High Glutathione Content
Anti-Aging Benefits

With a potent 2000mg of glutathione, it packs a serious punch in the skin-brightening game.

Its claims to reduce dark spots and hyperpigmentation make it a standout choice for those seeking a more even skin tone.

Plus, the added anti-aging benefits keep your skin looking youthful, smooth, and radiant.

Being vegan, cruelty-free, and manufactured in the USA gives us extra confidence in its quality and safety.

While some user results vary, the value-packed jar of 120 capsules makes it a convenient pick for a skin refresh and glow boost.

Be sure to also check out the best glutathione and collagen supplement for more options! Also, here is the price history so you know exactly when to buy!

Price history for Northern Crown Cosmetics Glutathione Pills on Amazon

Best for Anti-Aging: Codeage Liposomal Glutathione

Codeage Liposomal Glutathione Supplement - Pure Reduced Setria L-Glutathione, Liposomal Delivery, Phospholipid Complex - Encapsulated Glutathione Powder Pills - Vegan, Non-GMO - 60 Capsules
Highlights
High-potency dosage
Liposomal delivery system
Easy-to-swallow capsules

As the best for anti-aging, its liposomal delivery maximizes bioavailability, ensuring your skin gets the antioxidant support it needs.

With a powerful 500 mg of pure Setria L-Glutathione per capsule, it packs a serious punch against oxidative stress, which is key for melasma reduction.

Plus, the easy-to-swallow capsules make daily dosing hassle-free.

While some users might experience mild stomach upset or need to eat with it, the overall quality, purity, and USA-made standards make it a top contender.

It's a smart choice if you're serious about brightening your skin and turning back the clock.

Be sure to also check out the best creatine for teens for more options! Also, here is the price history so you know exactly when to buy!

Price history for Codeage Liposomal Glutathione on Amazon

Best for Hyperpigmentation: GlocalCare Depigma

GlocalCare Depigma Support Reduction of Hyperpigmentation, Melasma & Dark Spots with Glutathione, Polypodium Leucotomos, Grape Seed & Marigold Extract
Highlights
Natural, chemical-free ingredients
Visible skin improvements
Addresses internal imbalances

Depigma GlocalCare is specifically formulated to combat hyperpigmentation from within by combining potent natural extracts like Polypodium Leucotomos, Grape Seed, and Marigold with the power of Setria L-Glutathione.

This science-backed blend works synergistically to brighten skin, reduce dark spots, and even out skin tone without harsh chemicals.

Plus, it offers additional benefits like improved hydration, anti-wrinkle effects, and protection from environmental radiation.

While results can take some time, its premium, all-natural ingredients make it a safe and promising choice for those seeking long-lasting skin clarity.

Be sure to also check out the best glutathione powder for skin whitening for more options! Also, here is the price history so you know exactly when to buy!

Price history for GlocalCare Depigma on Amazon

Vaite

Glutathione Supplement for Whitening Skin - Anti-Aging, Perfect Vegan Blend with L-Glutathione Supplements, Vitamin C - 90000 mg - 120 Capsules - Antioxidant Effect for Women and Men
Highlights
Supports Skin Glow
Organic Ingredients
Contains Antioxidants

VAITE's Glutathione capsules deliver a hefty dose of 90,000 mg of powerful antioxidants, designed to combat free radicals and support a radiant, even complexion.

The inclusion of organic lemon and mulberry extracts adds a natural touch, making it suitable even for sensitive skin.

Plus, the convenient capsule form makes daily supplementation easy and mess-free.

While some users report mixed results and slight color changes in capsules, the overall support for skin glow and antioxidant protection makes it a solid choice for those seeking a clean, effective skincare boost.

Be sure to also check out the best vitamins for lactating dogs for more options! Also, here is the price history so you know exactly when to buy!

Price history for Vaite on Amazon

TOSOWOONG Arbutin Cream

Arbutin 7% + Tranexamic Acid 4% Cream, 70,000ppm Arbutin, 40,000ppm TXA, Niacinamide, Glutathione, Dark Spots, Freckle, Blemishes, Pigmetation, Korean Skin Care, 50ml, 1.69 fl.oz.
Highlights
Effective hyperpigmentation reduction
Gentle, suitable for all skin
Fast-absorbing, non-sticky

The high-concentration cream with 7% Arbutin delivers noticeable results in fading pigmentation, especially when it comes to stubborn melasma patches.

Its powerful blend of ingredients, including Glutathione, helps boost skin clarity and accelerate healing without irritating sensitive skin types.

Plus, the fast-absorbing, non-sticky finish makes it easy to incorporate into your daily routine.

While results may take some patience, the gentle formula ensures safe, consistent use.

Overall, a smart choice for those seeking a mild yet effective solution for pigmentation concerns, with good user ratings backing its quality.

Be sure to also check out the best lactation powder for more options! Also, here is the price history so you know exactly when to buy!

Price history for TOSOWOONG Arbutin Cream on Amazon

Lilymoon Glutathione for Melasma

Glutathione Whitening Pills Skin Lightening Pills - Skin Whitening Formula - Glutathione Whitening Skin Pills with Vitamin C - Skin Lightener - Dark Spot Remover - Made in USA
Highlights
Effective skin whitening
High-quality USA made
Easy to swallow

LILYMOON’s Glutathione Pills offer effective skin whitening and a radiant glow, thanks to high-quality ingredients made in the USA.

The capsules are easy to swallow and suit those looking for a natural way to brighten their skin tone.

While results can vary and some users might experience peeling, the overall benefits of antioxidant support and anti-aging effects make this a solid choice.

Keep in mind the larger capsule size—it's manageable but may take some getting used to.

If you're seeking a trusted, in-the-USA supplement for melasma, this one deserves a spot on your list.

Be sure to also check out the best vitamins for traveling for more options! Also, here is the price history so you know exactly when to buy!

Price history for Lilymoon on Amazon

Lillybright Naturals

Glutathione Capsules - 1,500mcg Glutathione Supplement - Skin Tone Enhancer - Targets Dark Spots & Acne Marks - Potent Antioxidant - 60 Capsules
Highlights
Even skin tone
Natural ingredients
Supports immune health

The gentle formulation aims to even skin tone and diminish dark spots, making it a nice option for those with melasma seeking a natural approach.

Packed with antioxidants like ginger and cinnamon, this vegan-friendly capsule not only targets skin concerns but also supports your immune system and liver health.

Made in a GMP-certified U.

S. facility, it guarantees quality.

However, keep in mind that potency can vary and results are somewhat mixed across users.

The small bottle makes it a convenient trial size, but some might want a larger supply for ongoing use.

Be sure to also check out the best supplement for methylation for more options! Also, here is the price history so you know exactly when to buy!

Price history for Lillybright Naturals on Amazon

TOSOWOONG Glutathione Serum

Glutathione Serum with 20,000ppm Glutathione, Niacinamide and hyaluronic acid, Dark Spot, Improve skin elasticity, Revitalize complexion, Korean Skincare, 30ml, 1.01 fl. oz.
Highlights
High 99% purity
Visibly reduces wrinkles
Deeply hydrates skin

Its 99% purity ensures maximum efficacy, giving your skin the full punch of glutathione's skin-brightening powers.

The inclusion of hyaluronic acid adds a lovely, deep hydration boost that helps diminish fine lines and wrinkles, leaving your complexion looking more youthful and radiant.

However, the serum does have a strong odor that some may find off-putting, and its high concentration could potentially irritate sensitive skin.

Despite this, if you're seeking a potent, results-driven glow booster, this serum is definitely worth considering on your skincare journey.

Be sure to also check out the best gummies for female arousal for more options! Also, here is the price history so you know exactly when to buy!

Price history for TOSOWOONG Glutathione Serum on Amazon

Toniiq Glutathione for Melasma

Toniiq Ultra High Strength Glutathione Capsules - 1000mg Concentrated Formula - 98%+ Highly Purified and Bioavailable - Non-GMO Fermentation - 60 Capsules Reduced Glutathione Supplement
Highlights
High purity (98%+)
Supports skin brightening
Easy to swallow capsules

The 1000mg of reduced glutathione packed into each capsule is really potent, promising significant antioxidant support that can help target melasma.

The 98% purity ensures you're getting a high-quality dose without fillers or unnecessary additives.

Plus, it's sustainably produced through non-GMO fermentation, aligning with eco-conscious values.

The capsules are easy to swallow, making daily support hassle-free.

Though it’s on the pricier side, the rigorous third-party testing and GMP-certified manufacturing give us confidence in its consistency and safety.

For those dedicated to brighter, clearer skin, this one’s worth considering.

Be sure to also check out the best vitamins for sensitive stomach for more options! Also, here is the price history so you know exactly when to buy!

Price history for Toniiq on Amazon

Celdyque

Pure Glutathione Concentrate Mix-in Serum 30,000 ppm w/Niacinamide & Hyaluronic Acid Ceramide | Evens Skin Tone Reduces Hyperpigmentation Acne Scars Dark Spots for Sensitive Skin Korean Skincare
Highlights
Effective hyperpigmentation reduction
Gentle on skin
Quick visible results

Formulated with a hefty 30,000 ppm of Glutathione, it truly delivers on brightening and evening out skin tone.

It zooms in on stubborn hyperpigmentation, fading dark spots from sun damage or acne scars, and helps your skin look healthier and more radiant.

Plus, with ingredients like Niacinamide, Hyaluronic Acid, and Ceramides, it hydrates intensely while strengthening your skin’s natural barrier.

The serum is gentle and effective, providing visible results in just a few weeks.

The only minor caveat?

It can feel a bit tacky after application, but that’s a small trade-off for the glow it provides.

Be sure to also check out the best l-methionine supplement for more options! Also, here is the price history so you know exactly when to buy!

Price history for Celdyque on Amazon

Ebanel

Ebanel Dark Spot Remover for Face Peel Skin Brightening Cream Melasma Hyperpigmentation Treatment Sun Spot Age Spots Freckle Remover Fade Cream, Synovea, 4-Butylresorcinol, Niacinamide, Glutathione
Highlights
Visible brightening effects
Effective pigment inhibitors
Good for all skin tones

It combines potent ingredients like Synovea HR and 4-Butylresorcinol, both clinically proven to brighten skin and tackle pigmentation.

The inclusion of skin brighteners such as Glutathione, Niacinamide, and Kojic Acid means it's designed for noticeable fading of dark spots and uneven tone.

Plus, it's versatile enough to use on multiple areas—face, neck, even elbows.

While results can vary and patience is key, the visible brightening effect makes it a solid choice for those battling melasma.

Expect consistency, and you might just see your glow return.

Be sure to also check out the best luteolin supplement for more options! Also, here is the price history so you know exactly when to buy!

Price history for Ebanel on Amazon

Pharmlitalia Glutathione for Melasma

Melasma Treatment for Face - Melasma Cream & Age Spot Remover for Skin Discoloration, Post-Blemish Marks, Scars & Spots | Dark Spot Remover for Face & Body
Highlights
Gentle, no redness
Hydrating formula
Lightening effectiveness

Its gentle yet effective formulation makes it suitable for sensitive skin, providing hydration without causing redness—an often overlooked perk.

It gradually brightens dark patches and hyperpigmentation, giving your skin a subtle glow over time.

While some users have reported mixed results and a few skin rash episodes, most appreciate its lightening prowess and dermatologist backing. If you're after a thoughtful, hydrating option that aims to fade melasma without harsh chemicals, this cream is worth considering—just remember, patience and patch testing are key!

Be sure to also check out the best luteolin supplements for more options! Also, here is the price history so you know exactly when to buy!

Price history for Pharmlitalia on Amazon

APLB

APLB Glutathione Niacinamide Body Lotion | LIPO GLUTA NIAC CEN™ 12.5% 10.14 FL.OZ/Korean Skincare, Long lasting hydration, Revitalize for gentle and improve skin texture
Highlights
Good for sensitive skin
Easy absorption
Contains antioxidants

The LIPO GLUTA NIAC CEN lotion offers a powerful combo of glutathione and niacinamide, both renowned for their brightening effects on melasma.

The addition of Centella Asiatica Extract and the Centella 3x Complex helps soothe sensitive skin while working to even out skin tone.

With hydrating ingredients like Hyaluronic Acid and Beta Glucan, it keeps your skin moisturized and glowing.

Plus, it's lightweight and absorbs quickly, making it perfect for daily use.

While the bottle is small and it lacks fragrance, its antioxidant-rich formula makes it a solid choice for long-term melasma battle.

Be sure to also check out the best creatine chews for more options! Also, here is the price history so you know exactly when to buy!

Price history for APLB on Amazon

Ultra Herbs

Glutathione Supplement Active Reduced Form, Enriched with Resveratrol, NAC, Collagen, Hyaluronic Acid, Vitamin C - Advanced Antioxidant for Immunity & Detox | 150 Capsules
Highlights
Comprehensive 7-in-1 blend
Easy once daily dose
Made in the USA

Ultra Herbs Glutathione offers a comprehensive 7-in-1 blend that targets your overall vitality and skin health.

It's designed for easy, once-daily use, making it hassle-free to stay consistent.

Made right here in the USA, you can trust the quality and safety standards backing this supplement.

While some might wish for higher ingredient dosages and sleeker packaging, the value of 150 capsules per bottle means you'll be stocked for months.

Perfect for those seeking an all-in-one approach to brightening and supporting skin from within!

Be sure to also check out the best galantamine supplement for more options! Also, here is the price history so you know exactly when to buy!

Price history for Ultra Herbs on Amazon

Orinthalixium Glutathione Gummies Glutathione for Melasma

Liposomal Glutathione Gummies 1000MG - Reduced L-Glutathione for Antioxidant - Sugar Free Glutathione Supplement with Vitamin C, Vegan Collagen Gummies for Liver Detox, Glowing Skin - 150 Gummies
Highlights
High Potency Dosage
Enhanced Absorption
Natural Flavors

Our team loves the powerhouse formula packed into each gummy.

With a whopping 1000mg of Liposomal L-Glutathione, it offers superior absorption thanks to cutting-edge liposomal technology, which is a game-changer for skin clarity and antioxidant defense.

Plus, its proprietary vegan collagen blend and organic Camu Camu vitamin C work synergistically to boost radiance and reinforce skin health from within.

The exotic dragon fruit flavor makes the experience enjoyable, even if the chewiness is a tad intense.

Overall, it's a delicious, potent option if you're serious about tackling melasma naturally.

Be sure to also check out the best gluten pills for more options! Also, here is the price history so you know exactly when to buy!

Price history for Orinthalixium Glutathione Gummies on Amazon

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