Best Multivitamin with Methylfolate
Looking for a multivitamin that offers more than just the basics? Dive into our curated selection of the best multivitamin with methylfolate, where nourishing your body with essential nutrients becomes a swift, satisfying journey. Whether you're boosting brain power or supporting overall wellness, we've got the perfect pick to elevate your daily routine.
Top Frugal Selection: Envitamin

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Liquid capsule for absorption |
Contains 23 vitamins and minerals |
Includes fruit and vegetable blend |
Ultimate Multivitamin by envitamin shines with its unique liquid capsule format, ensuring maximum absorption—a real game-changer for bioavailability.
Packed with 23 essential vitamins and minerals plus a proprietary blend of 42 fruits and vegetables, it offers comprehensive support in a small, convenient package.
While it’s a bit modest in size and slightly lean on vitamin content compared to pricier options, its affordability makes it perfect for budget-conscious shoppers.
Overall, this multivitamin proves that you don’t need to spend a fortune for high-quality, effective daily support.
Be sure to also check out the best multivitamin without gelatin for more options! Also, here is the price history so you know exactly when to buy!

Best for Immune Support: SmartyPants

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High-quality, science-backed ingredients |
Delicious natural flavors |
Third-party tested for purity |
This gummy is a powerhouse of 21 nutrients, expertly formulated for women with busy lifestyles.
We love that it uses bioavailable forms like methylfolate and methylcobalamin, making absorption a breeze for your body.
The added Vitamin D3 and Zinc boost immune support, earning it our "Best for Immune Support" badge.
Plus, the natural blueberry, orange, and lemon crème flavors make taking your daily dose a treat — even if you’re not a fan of sticky textures or metallic tastes.
Overall, it offers a delicious, reliable, and clean option for anyone looking to fill their nutrient gaps efficiently.
Be sure to also check out the best multivitamin for vegan female for more options! Also, here is the price history so you know exactly when to buy!

Best for Cognitive Function: Pure Encapsulations O.N.E. Multivitamin

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High bioavailability |
Supports cognitive health |
Free from common allergens |
**Pure Encapsulations’ O.
N.
E.
Multivitamin** truly shines as the best for cognitive function, thanks to its well-rounded blend of brain-boosting ingredients like lutein, zeaxanthin, and CoQ10, paired with methylfolate for optimal mental clarity.
It offers high bioavailability, meaning your body absorbs these nutrients efficiently — a big plus for busy individuals.
Plus, it supports overall eye and cellular health while being free from common allergens.
The distinct odor and higher price tag are minor downsides given its premium formulation.
Overall, a smart choice for mental sharpness!
Be sure to also check out the best multivitamin for vegetarians for more options! Also, here is the price history so you know exactly when to buy!

Best for Natural Absorption: Thorne Basic Nutrients 2/Day

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High absorption nutrients |
Third-party tested |
Trusted brand |
… Formulated with highly bioavailable forms of vitamins, including methylated B-vitamins and minerals, this supplement truly lives up to its label as the "Best for Natural Absorption." The third-party testing certification guarantees purity, giving us confidence in what’s inside each capsule.
While some users might find the smell a bit strong or experience mild nausea if taken on an empty stomach, the fundamental support for heart, brain, immune, and skin health is clear.
For those prioritizing bioavailability and trusted quality, this is a stellar choice.
Be sure to also check out the best multivitamin for pcos for more options! Also, here is the price history so you know exactly when to buy!

Thorne

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Supports methylation |
Active B vitamins |
Trusted high-quality brand |
Methyl-Guard Plus by Thorne stands out with its active forms of B vitamins and methylated folate, ensuring optimal absorption and support for healthy methylation.
It’s a powerhouse for maintaining homocysteine levels and promoting overall wellness.
Plus, it's free from common allergens like gluten, dairy, and nuts, making it a versatile choice for various diets.
Trusted by elite athletes and backed by collaboration with Mayo Clinic, Thorne's quality is second to none.
Though a bit on the pricier side, its premium ingredients make it worth considering for those serious about their supplement game.
Be sure to also check out the best multivitamin for shih tzu for more options! Also, here is the price history so you know exactly when to buy!

Triquetra Methyl Folate

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High potency dosage |
Bioactive methylfolate form |
Supports brain and mood |
Its high-potency 15mg of L-Methylfolate ensures potent support for methylation, making it ideal for those with absorption concerns or methylation issues.
The inclusion of Methylcobalamin B12 creates a dynamic duo that boosts energy, sharpens focus, and stabilizes mood.
Since methylfolate is in its active 5-MTHF form, it’s quickly absorbed and ready to work, especially beneficial for individuals with folate metabolism challenges.
While some users might experience mild heartburn, the benefits for brain health, cardiovascular support, and nerve function make it a premium choice for health-conscious supplement seekers.
Be sure to also check out the best multivitamin for women with pcos for more options! Also, here is the price history so you know exactly when to buy!

Igennus Multivitamin with Methylfolate

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Bioavailable methylfolate |
Easy to swallow |
Supports energy & immunity |
The bioavailable methylfolate stands out, easily crossing cell membranes to deliver maximum benefits.
The formula is crafted with clean, hypoallergenic ingredients—no fillers or synthetic junk here—so it's gentle yet effective.
The high-potency blend of iron, B-vitamins, and essential nutrients provides all-day support for energy, immunity, and hormone balance.
Plus, the sustained-release tablets ensure steady nutrient absorption throughout the day.
While it’s ideal for many women, postmenopausal users should note the iron content might not be suitable.
Overall, a premium choice for those seeking faster, targeted results in their multivitamin.
Be sure to also check out the best probiotic with butyrate for more options! Also, here is the price history so you know exactly when to buy!

Pure Therapro Rx Methyl Multi

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High absorption bioavailability |
Supports MTHFR mutations |
No artificial ingredients |
The Pure TheraPro Rx Methyl Multi without Iron stands out with its superior absorption thanks to pre-methylated B12 and methylfolate, ideal for those with MTHFR mutations.
Made from high-quality, no-artificial ingredients, it’s a clean, vegan-friendly choice backed by rigorous third-party testing.
The capsules are designed for maximum bioavailability, ensuring your body gets what it needs efficiently.
Keep in mind, some may experience mild detox symptoms — patience and gradual dosing are key.
Overall, it’s a robust, thoughtfully formulated supplement perfect for supporting total wellness and vitality.
Be sure to also check out the best women's multivitamin without iodine for more options! Also, here is the price history so you know exactly when to buy!

Inessa

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Feels Effective and Boosts Mood |
Comprehensive Nutrient Profile |
Vegan and Allergen-Free |
This multivitamin truly feels effective, boosting both mood and energy levels thanks to its comprehensive nutrient profile.
With 25 highly bioavailable ingredients—including methylfolate, K2, and D3—it simplifies your daily routine by replacing multiple supplements.
Plus, it's vegan, allergen-free, and free from unnecessary additives, which makes it perfect for those who prioritize clean eating.
However, be prepared for a strong odor and a fluorescent urine color—quirks to know before you buy.
While it’s on the pricier side, the potent mix of nutrients can make it well worth the investment for sustained vitality and wellness.
Be sure to also check out the best bariatric multivitamin with iron for more options! Also, here is the price history so you know exactly when to buy!

Primal Harvest Multivitamin with Methylfolate

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Complete vitamin blend |
Supports energy levels |
Clean, gluten-free formula |
The Primal Multivitamin packs a punch with a comprehensive blend of 21 essential nutrients that boost energy, support immunity, and promote overall wellness.
Its clean, gluten-free formula aligns with diverse dietary needs, making it a reliable daily companion.
While it has a strong odor and only 1 capsule per day, it still provides targeted support without unnecessary fillers.
Keep in mind, its limited iron content might not suit everyone, but for those looking for a straightforward, well-rounded multivitamin, it’s a solid choice to energize your day and keep your health on track.
Be sure to also check out the best berberine with ceylon cinnamon for more options! Also, here is the price history so you know exactly when to buy!

SmartyPants

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Delicious tasting gummies |
High-quality, bioavailable nutrients |
Third-party tested purity |
SmartyPants Men's Multi & Omegas packs a punch with its delicious lemon crème, blueberry, and blackberry flavors—taking the hassle out of supplementing.
The gummies contain bioavailable nutrients like methylfolate and methylcobalamin, making absorption a breeze for your body.
Plus, it's third-party tested and awards like the Clean Label Project ensure you're getting a clean, safe product.
Just a heads-up, you’ll need to enjoy six gummies daily, and some organic versions may have a fishy aftertaste.
Overall, a tasty, trustworthy option for supporting your daily health!
Be sure to also check out the best magnesium threonate gummies for more options! Also, here is the price history so you know exactly when to buy!

Double Wood Methylated Multivitamin

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Methylated, bioavailable vitamins |
Supports healthy homocysteine |
Suitable for MTHFR mutation |
… Double Wood’s Methylated Multivitamin delivers only activated, bioavailable forms of essential vitamins—perfect for anyone needing support for MTHFR mutations or trying to optimize their homocysteine levels.
The inclusion of methylated B12, B6, and B2, along with methylated folate, ensures your body can actually use these nutrients without extra conversion steps.
Plus, it’s flexible—can be stacked with other multivitamins for a customized boost.
While the price is a bit higher, the quality and targeted support make it a smart choice for a clean, effective supplement routine.
Be sure to also check out the best vitamin d3 in olive oil for more options! Also, here is the price history so you know exactly when to buy!

Best Nest Wellness Men’s Multi Plus Multivitamin with Methylfolate

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Contains methylfolate |
Supports brain health |
Includes probiotics |
This multivitamin is tailored specifically for men, providing a comprehensive blend that supports everything from brain health to energy.
The inclusion of methylfolate and methylcobalamin really sets it apart, helping to boost focus, memory, and overall mental clarity.
Plus, with probiotics and digestive enzymes, it’s gentle on the stomach and promotes gut health.
The convenient once-daily caplet makes sticking to your routine effortless.
Just a heads-up—the flavor can be a bit strong, so those sensitive to taste might want to consider that.
Overall, a solid choice for men looking for an effective, all-in-one supplement.
Be sure to also check out the best vitamins for sensitive stomach for more options! Also, here is the price history so you know exactly when to buy!

Thorne

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Supports methylation health |
Boosts energy and mood |
Trusted quality brand |
Thorne’s multivitamin with methylfolate is a powerhouse for supporting healthy methylation, which is crucial for energy, mood, and cellular health.
It also promotes positivity and helps maintain nerves and circulation — essential for overall well-being.
Plus, with its focus on cardiovascular support by aiding homocysteine metabolism, it ticks all the right boxes.
As a trusted brand used by professional sports teams and collaborating with Mayo Clinic, Thorne offers dependable quality.
Though the review count is limited, its 4.7-star rating speaks volumes for those seeking premium, research-backed supplementation.
Be sure to also check out the best vitamins for lactating dogs for more options! Also, here is the price history so you know exactly when to buy!

Igennus Kids Multivitamin

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High absorption nutrients |
Clean, hypoallergenic ingredients |
Great taste for kids |
These gummies pack a punch with higher potency than your average multivitamin, delivering a solid boost of 11 essential vitamins and minerals, including methylated B-vitamins like folate and methylcobalamin B12, which are optimized for better absorption.
The clean, hypoallergenic formula means no artificial colors, flavors, or preservatives — perfect for health-conscious families.
Plus, their delicious berry flavor makes them a favorite among kids, turning supplement time into a treat.
The only caveat is that the potency might be too intense for some, so always start with the recommended dosage.
Be sure to also check out the best bariatric multivitamin chewable for more options! Also, here is the price history so you know exactly when to buy!

Envitamin
Multivitamin with Methylfolate

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Contains methylated folate |
High vitamin content |
Easy to swallow capsules |
The Methylated B12 and 5-MTHF make it a fantastic choice for those looking to support healthy methylation processes.
The easy-to-swallow capsules are a plus for anyone who dislikes pills, and the high vitamin content ensures you're getting essential micronutrients in one convenient scoop.
While it may not be as comprehensive as some other multivitamins, its targeted formula is perfect for busy lifestyles.
Just keep in mind the limited reviews and potential taste considerations.
Overall, a solid option for a methylfolate-rich multivitamin that’s quick and easy to incorporate into your routine.
Be sure to also check out the best vitamin d for bariatric patients for more options! Also, here is the price history so you know exactly when to buy!

Igennus Methylated Men’s Multivitamin

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High absorption formula |
Methylated B-vitamins |
Slow-release technology |
The methylated, bioactive forms of B-vitamins and other essential nutrients ensure optimal absorption, giving your cells a quick boost.
The slow-release formula distributes nutrients steadily throughout the day, maintaining balanced levels without the peaks and crashes.
Designed specifically for men, it offers a comprehensive mix of 22 high-potency ingredients minus the unnecessary fillers.
Plus, its clean, vegan-friendly profile and lab-verified ingredients make it a trustworthy choice.
While it skips magnesium and comes at a slightly higher price, its efficiency and quality make it a savvy pick for health-conscious men seeking reliable support.
Be sure to also check out the best liquid multivitamin men for more options! Also, here is the price history so you know exactly when to buy!

Pure Therapro Rx

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High absorption bioavailability |
Supports MTHFR mutations |
No artificial ingredients |
Pure TheraPro Rx Methyl Multi without Iron delivers high absorption with its pre-methylated forms of B12 and Folate, making it ideal for those with MTHFR mutations.
Its clean, vegan-friendly formula is free from artificial fillers, ensuring you get only the good stuff.
We appreciate the careful formulation, promoting total-body wellness and supporting cognitive and detox functions.
However, new users should start slow, as some may experience detox symptoms—a sign your body is adapting.
Overall, this supplement is a top-choice for bioavailability and purity, perfect for anyone prioritizing quality and effective absorption.
Be sure to also check out the best vitamin b12 supplement for dogs for more options! Also, here is the price history so you know exactly when to buy!
