15 Best Prenatal Vitamins with Methylfolate for Expecting Moms

Discover the best prenatal vitamins with methylfolate, blending essential nutrients into a concise guide to support your pregnancy journey effortlessly.
BrandMy RatingPrice
Smartypants
Best Cheap Pick
8.8/10
Zahler
Best for Folic Acid Absorption
9.2/10
Igennus Healthcare Nutrition
Best for Sensitive Stomachs
8.8/10
Maryruth Organics
Best for Whole Nutrition
9.4/10
New Chapter
9.2/10

Best Prenatal Vitamins with Methylfolate

Navigating the world of prenatal vitamins can feel like decoding a complex map, especially when searching for those that pack a powerful punch of methylfolate. For expectant mothers eager to support both their health and their baby’s development, finding the perfect supplement is essential—quickly, clearly, and confidently. Here’s our guide to the best prenatal vitamins with methylfolate—bright, straightforward, and ready to illuminate your path to prenatal wellness.

Best Cheap Pick: SmartyPants

SmartyPants Prenatal Vitamins for Women, Multivitamin Gummies: Omega 3 Fish Oil (EPA/DHA), Biotin, Methylfolate, Vitamin D3, C, Vitamin B12, B6, A, K & Zinc, Inositol, 120 Count (30 Day Supply)
Highlights
Rich in essential nutrients
Methylfolate for fetal health
Delicious, easy to take

SmartyPants Prenatal Multi & Omegas stands out as a delicious and convenient option, packed with 19 essential nutrients including bioavailable methylfolate—crucial for fetal development.

Its engaging flavors like Lemon, Orange, and Strawberry Banana make taking supplements seem less like a chore.

Plus, it's third-party tested and certified clean, prioritizing quality and safety.

However, the added sugar and multiple gummies per day might not suit everyone.

Still, for quality, taste, and affordability, it’s a smart, well-rounded choice for expecting moms seeking flexibility and trustworthiness.

Be sure to also check out the best multivitamin with methylfolate for more options! Also, here is the price history so you know exactly when to buy!

Price history for SmartyPants on Amazon

Best for Folic Acid Absorption: Zahler Prenatal Vitamin

Zahler Prenatal Vitamin with DHA & Folate - DHA Supplements & Prenatal Multivitamin for Mother and Child - Kosher Prenatal DHA Prenatal Vitamins with Iron, Pre Natal Softgels 60 Count
Highlights
Body-ready methylfolate
Includes DHA + nutrients
Easy to swallow softgels

Zahler Prenatal Vitamin with DHA & Folate truly shines when it comes to methylfolate absorption.

The natural, body-ready form of folate ensures your body can utilize it efficiently, which is a game-changer for women who struggle with unmetabolized folic acid.

Plus, the 300mg of DHA supports both mom and baby’s brain development, making it a comprehensive prenatal choice.

The softgel format makes swallowing effortless, even during pregnancy, and the premium quality ingredients guarantee peace of mind.

Slight fishy aftertaste and packaging concerns are minor quibbles considering its top-tier nutritional profile.

Be sure to also check out the best prenatal vitamins with coq10 for more options! Also, here is the price history so you know exactly when to buy!

Price history for Zahler Prenatal Vitamin on Amazon

Best for Sensitive Stomachs: Igennus Methylated Prenatal

Igennus Methylated Prenatal Multivitamin for Women, Folate for MTHFR, High Absorption, Clean Label, Gentle Iron, Choline, Calcium & Magnesium, Vegan Pregnancy Vitamins, Halal, Non-GMO, 60 Tablets
Highlights
Methylated B-vitamins included
Pure, lab-tested ingredients
Gentle on stomach

The Igennus Methylated Prenatal Multivitamin is our top pick for "Best for Sensitive Stomachs" thanks to its thoughtfully gentle, high-quality ingredients.

The methylated B-vitamins and chelated minerals are designed for optimal absorption, making them easier on digestion.

Plus, it’s free from nasty fillers, heavy metals, and retinol, aligning perfectly with those seeking a clean, safe supplement.

Small, two-tablet dose ensures consistent coverage without overwhelming your gut.

While it comes at a slightly higher price, the pure, lab-tested quality and comprehensive nutrient support make it a worthwhile investment for moms-to-be aiming for gentle, effective prenatal support.

Be sure to also check out the best prenatal vitamins for vegans for more options! Also, here is the price history so you know exactly when to buy!

Price history for Igennus Methylated Prenatal on Amazon

Best for Whole Nutrition: MaryRuth Organics Prenatal Gummies

MaryRuth Organics Prenatal Vitamins for Women | USDA Organic Prenatal Gummies | Postnatal Vitamins for Women Breastfeeding | Methylfolate 800 mcg DFE | Iodine | Vegan | Non GMO | 30 Servings
Highlights
Great taste and texture
No stomach upset
Contains methylfolate

MaryRuth Organics Organic Prenatal Gummies stand out as the best for whole nourishment.

With 800 mcg of methylfolate, they support healthy neural tube development, reducing the risk of birth defects.

Plus, they boast a broad spectrum of essential vitamins including B12, C, D, and minerals like iodine and zinc, all in a delicious strawberry flavor.

The gummies are vegan, organic, non-GMO, and free from common allergens, making them suitable for diverse lifestyles.

While they come at a higher price and offer limited servings, the quality, taste, and comprehensive nutrient profile make these gummies a great choice for expectant moms seeking complete prenatal support.

Be sure to also check out the best prenatal vitamin for mthfr mutation for more options! Also, here is the price history so you know exactly when to buy!

Price history for MaryRuth Organics Prenatal Gummies on Amazon

New Chapter Prenatal

New Chapter Prenatal Vitamins, One Daily Prenatal Multivitamin with Methylfolate + Choline for Healthy Mom & Baby, Gluten Free & Non-GMO, 30 Count
Highlights
Contains methylfolate
Gentle on stomach
Convenient once daily

ONE DAILY Prenatal offers fermented nutrients that are super gentle on your stomach, making it easy to take anytime—even on an empty stomach.

The inclusion of methylfolate and choline supports your baby's development and boosts your immune health.

Although the initial taste can be a bit strong, the convenience of a once-daily capsule makes up for it.

Keep in mind, it provides moderate iron, so if you're concerned about iron intake, you might need a separate supplement.

Overall, a simple, clean choice for expecting moms prioritizing ease and quality.

Be sure to also check out the best prenatal vitamin for vegetarians for more options! Also, here is the price history so you know exactly when to buy!

Price history for New Chapter Prenatal on Amazon

Thorne Basic Prenatal

THORNE Basic Prenatal - Well-Researched Folate Multi for Pregnant and Nursing Women Includes 18 Vitamins and Minerals, Plus Choline - 90 Capsules - 30 Servings
Highlights
High-quality ingredients
Bioactive folate (5-MTHF)
Supports brain development

Thorne’s Basic Prenatal delivers bioactive 5-MTHF, ensuring optimal absorption for women who need it most.

It combines well-absorbed nutrients like choline—crucial for your baby's brain and neurological development—with gentle ingredients that may help ease morning sickness.

Trusted by thousands of health professionals and top athletic teams, Thorne's quality is hard to beat.

While it does come with a potent smell and requires multiple capsules, the high-quality ingredients and focus on effective, supportive nutrition make it an excellent choice for pre-conception through nursing.

Be sure to also check out the best postnatal vitamins not breastfeeding for more options! Also, here is the price history so you know exactly when to buy!

Price history for Thorne Basic Prenatal on Amazon

Pink Stork Prenatal Vitamins with Methylfolate

Pink Stork Total Prenatal Vitamins with DHA, Folate, Iron, Choline, and Vitamin B12 - Prenatals for Women to Support Fetal Development, Pregnancy Must Haves, Berry Essence, 60 Capsules, 1 Month Supply
Highlights
Contains 14 essential nutrients
Easy to swallow capsules
Women-owned brand

Pink Stork Total Prenatal with DHA really covers all the bases with 14 vital nutrients, including methylfolate—crucial for preventing neural tube defects.

The capsules are small and easy to swallow, perfect for those queasy mornings.

Plus, the inclusion of omega-3 DHA supports your baby's brain and eye development right from the start.

We love that it’s women-owned and third-party tested, giving peace of mind.

While some users report mild digestive issues or a noticeable scent, overall, this prenatal is a solid pick for expecting moms who want comprehensive, trustworthy support in just two capsules a day.

Be sure to also check out the best multivitamins with probiotics for more options! Also, here is the price history so you know exactly when to buy!

Price history for Pink Stork on Amazon

Mama's Select Prenatal Vitamins

Mama's Select Prenatal Vitamins for Women – Allergen-Free, MTHFR Friendly, Methylated Folate & B Vitamins, Easy-to-Digest, Supports Fetal Development, Once Daily, Vegan, No Biotin
Highlights
Easy to swallow
Contains methylfolate
Gentle on stomach

The capsules are super easy to swallow, which is a real win during pregnancy when even swallowing pills can be a challenge.

The inclusion of methylfolate is a standout feature — it's a more bioavailable form of folate that supports optimal prenatal health.

Plus, this supplement is gentle on the stomach, reducing the risk of nausea or discomfort.

However, we did notice the limited product details and the absence of extra nutrients like iron or vitamin D, which are often important during pregnancy.

Availability can also be a bit tricky depending on where you shop.

Still, for straightforward methylfolate support, this one’s a solid choice.

Be sure to also check out the best multivitamins without biotin for more options! Also, here is the price history so you know exactly when to buy!

Price history for Mama's Select Prenatal Vitamins on Amazon

Ritual

Ritual Essential for Women Prenatal Multivitamin: Folate & Choline for Neural Tube Support, Omega-3 DHA for Fetal Brain Development, Iron, Calcium-Helper D3 & K2, Non-GMO, Vegan, Citrus, 30 Days
Highlights
Easy to swallow capsules
Contains methylfolate
Good flavor options

The Essential for Women Prenatal Multivitamin truly stands out with its traceability—ingredients sourced from Italy, Nova Scotia, Missouri, and Utah, ensuring quality at every step.

The smart capsule technology makes taking your daily dose effortless, with delayed-release capsules that enhance absorption.

Plus, the inclusion of methylfolate supports brain and heart health, which is essential during pregnancy.

While some might find the fishy aftertaste a bit pesky—and the price on the higher side—its clean, vegan, non-GMO formula and third-party testing make it a trustworthy choice for expecting moms who want the best.

Be sure to also check out the best multivitamin without gelatin for more options! Also, here is the price history so you know exactly when to buy!

Price history for Ritual on Amazon

Best Nest Wellness Prenatal Vitamins with Methylfolate

Best Nest Wellness Mama Bird Prenatal Multi Plus - Prenatal Care Supplement Supports Brain & Digestive Health - Vegan Multivitamin with L-Methylfolate, Probiotics & More - 30 Caplets (30 Servings)
Highlights
Complete prenatal support
Includes methylfolate
Vegan and easy-to-take

Complete supportive nutrition meets convenience with this vegan capsule that covers all your bases—folate, B12, iron, choline, zinc, and vitamin D3.

Plus, it’s packed with herbs and probiotics to help keep your digestion happy during pregnancy.

The inclusion of methylfolate specifically benefits your baby's brain development, which is a thoughtful touch.

The once-daily formula makes it easy to adopt into your routine, though the price is on the higher side, and the pills have a noticeable odor.

Still, if you're seeking comprehensive, plant-based support, this one's a strong contender.

Be sure to also check out the best postnatal vitamins for more options! Also, here is the price history so you know exactly when to buy!

Price history for Best Nest Wellness on Amazon

Honest Love the Bump Prenatal

The Honest Company Love the Bump Prenatal Once Daily Supplement | NSF-Certified, Non-GMO | 30 Count Tablets
Highlights
Complete prenatal support
Easy once-a-day pill
Organic & bioavailable

The Honest Company's prenatal vitamin offers comprehensive support with organic, highly bioavailable nutrients that truly back up its claims.

It's carefully crafted to help nurture a healthy pregnancy and fetal development, all in an easy once-a-day dose.

While the large, chalky pill might not win any beauty contests in your pill box, its non-GMO, clean ingredients make it a standout choice.

Certified by NSF and reviewed by health pros, it’s a reliable, ethical pick for expecting moms seeking peace of mind in their supplement routine.

Be sure to also check out the best multivitamin without iron for more options! Also, here is the price history so you know exactly when to buy!

Price history for Honest Love the Bump Prenatal on Amazon

MegaFood Baby & Me 2

MegaFood Baby & Me 2 Prenatal Multi - Prenatal Vitamins for Women Before & During Pregnancy with Choline, Methyl Folate, and Iron - Dr. Formulated, Gluten-Free, Vegetarian - 60 Tablets, 30 Servings
Highlights
Contains methylfolate
Made with real food
Doctor formulated

It packs a powerful punch with methylfolate and 2.5X more choline than most prenatal options, giving your baby's brain a boost right from the start.

Made with real food and crafted with care, it delivers 23 essential nutrients plus botanicals like orange, carrot, and cabbage to support overall wellness.

The doctor-formulated blend includes bioavailable methylated B12 and nourishing Vitamin D3, promoting better absorption.

While the large pill size and slightly bitter taste might be hurdles, it's still a top choice for those seeking high-quality, ethically made prenatal support—without DHA, but easily supplemented separately.

Be sure to also check out the best multivitamin without b6 for more options! Also, here is the price history so you know exactly when to buy!

Price history for MegaFood Baby & Me 2 on Amazon

Garden of Life Prenatal Prenatal Vitamins with Methylfolate

Garden of Life Organics Prenatal Vitamin: Folate for Energy & Healthy Fetal Development, Non-constipating Iron, Vitamin C, B6, B12, D3 – Organic, Non-GMO, Gluten-Free, Vegan, 30 Day Supply
Highlights
Whole food based
Vegan & organic
Easy to digest

TEND THE GARDEN stands out with its whole food approach, blending over 30 organic fruits, veggies, and herbs that keep nutrients natural and bioavailable.

The vegan and certified organic credentials give us confidence that mom and baby are getting clean, plant-based nourishment.

Plus, the easy-to-digest, fast-dissolving tablets make swallowing effortless—even with the size.

While it doesn’t include DHA, its organic, non-GMO profile and gentle formula make it an excellent choice for those seeking a clean, plant-powered prenatal supplement.

Be sure to also check out the best multivitamin without vitamin d for more options! Also, here is the price history so you know exactly when to buy!

Price history for Garden of Life Prenatal on Amazon

Mother's Promise

Prenatal Vitamin Gummies with DHA | Vegan Prenatal Vitamins for Women with Omega 3, Methylfolate, Choline & D3, Pregnancy Vitamins for Fetal Development | Gummy Multivitamin Supplement, 120 Count
Highlights
Delicious natural flavors
Vegan and plant-based
Easy to take gummies

These delicious natural flavors make taking your prenatal vitamins a treat rather than a chore.

The vegan and plant-based ingredients align perfectly with a clean, ethical lifestyle, and the gummies are super easy to incorporate into your daily routine.

While the nutrient dosage is somewhat moderate—so you might consider additional supplements during pregnancy—their focus on supporting moms preconception, pregnancy, and lactation makes them versatile.

Plus, knowing they are non-GMO, allergen-free, and lab-tested provides peace of mind.

Overall, a tasty, thoughtful option for supporting your growing family.

Be sure to also check out the best multivitamin without vitamin a for more options! Also, here is the price history so you know exactly when to buy!

Price history for Mother's Promise on Amazon

MegaFood

MegaFood Baby & Me 2 Prenatal Vitamin & Minerals - Vitamins for Women - with Folate (Folic Acid Natural Form), Choline, Iron, Iodine, Vitamin C, Vitamin D and More - 120 Mini Tabs (30 Servings)
Highlights
Whole food ingredients
Contains methylfolate
Easy to swallow mini tablets

MegaFood’s Daily Prenatal delivers a robust blend of 23 essential nutrients, emphasizing whole food ingredients like broccoli, carrots, and oranges for a natural touch.

The inclusion of methylfolate and B12 ensures optimal absorption, especially for those tricky genetic variations.

The mini tablets are a breeze to swallow, making daily intake effortless—even on an empty stomach.

Plus, it’s non-GMO, vegetarian, allergen-free, and tested for purity, giving peace of mind.

While the aftertaste isn’t the best, its clean, food-based approach makes it a standout choice for health-conscious mamas-to-be.

Be sure to also check out the best multivitamin without vitamin e for more options! Also, here is the price history so you know exactly when to buy!

Price history for MegaFood on Amazon

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