Best Probiotic for Colic
Struggling to soothe a colicky baby can feel like navigating a whirlwind of sleepless nights and endless worries. Discovering the perfect probiotic can bring a gentle, calming tide to your routine, helping restore balance and comfort. In this guide, we'll explore the best probiotic options to ease colic and bring peaceful days back to your little one.
Best for Soothing Colic: BioGaia
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| Soothes colic & fussiness |
| Safe for newborns |
| Natural breast milk ingredients |
BioGaia Protectis Baby Probiotic Drops are the most studied probiotic for colic, with a proven track record of calming fussiness and soothing tiny tummies.
Made from natural ingredients found in breast milk, it’s safely suited for newborns from day one, whether breastfed or bottle-fed.
While it may take a few days to notice a difference, many parents appreciate its gentle, natural approach without any artificial additives.
Though the servings are limited, the reassuring DIY of scientifically validated relief makes BioGaia our top choice for colic soothing.
Be sure to also check out the best probiotic for lactose intolerance for more options! Also, here is the price history so you know exactly when to buy!
Best for Gentle Digestion: Pink Stork Baby Probiotics
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| Supports digestion and immune health |
| Easy no-drip syringe |
| Vegan and non-GMO |
Pink Stork Baby Probiotic Drops earn our spot as the "Best for Gentle Digestion." Packed with Lactobacillus rhamnosus, the most-studied probiotic strain for little tummies, these drops are a gentle way to support your baby's digestive system and reduce fussiness from gas or constipation.
The no-drip syringe makes dosing a breeze, and the vegan, non-GMO formula reassures health-conscious parents.
While a few have reported packaging leakage, overall, this probiotic has shown promise in promoting gastrointestinal balance and immune health.
A reliable choice for your baby's comfort!
Be sure to also check out the best probiotics for liver for more options! Also, here is the price history so you know exactly when to buy!
Smart Budget Choice: MaryRuth Organic
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| Supports infant digestion |
| Unflavored, easy administration |
| Organic and clean label |
MaryRuth Organics USDA Organic Infant Liquid Probiotic Drops offer a robust blend of five probiotic strains, including Bacillus coagulans Unique IS-2, tailored specifically for a baby's delicate digestion.
The unflavored, easy-to-administer liquid makes it a hassle-free choice for busy parents.
Plus, with certifications like USDA Organic, Vegan, and Clean Label Project, it reassures us of its quality.
While the CFU count per dose is modest, this product provides gentle yet effective support for your infant's developing gut—a smart budget-friendly choice for nurturing your little one's health.
Be sure to also check out the best probiotic for histamine intolerance for more options! Also, here is the price history so you know exactly when to buy!
Lovebug Probiotics
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| Effective digestive relief |
| Includes vitamin D |
| Easy to incorporate |
Lovebug’s probiotic is formulated specifically for babies aged 0-12 months, addressing common issues like colic, gas, and digestive upset with six clinically studied strains.
The fact that it’s USDA Organic Certified and sugar-free means you can trust it’s safe and pure—no artificial ingredients or allergens here!
It also includes vitamin D, which is a bonus for immune support.
While the drops dispense quickly and lack a precise dosing dropper, the ease of use and effective relief make it a top choice for busy parents.
Overall, Lovebug’s gentle, high-quality formula is trusted by many moms for soothing little tummies.
Be sure to also check out the best probiotic for mouth ulcers for more options! Also, here is the price history so you know exactly when to buy!
Culturelle Baby
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| Clinically studied probiotics |
| Supports healthy digestion |
| Safe for infants |
Culturelle Baby Digestive Calm + Comfort Drops is from the #1 pediatrician-recommended probiotic brand, making it a top choice for anxious parents.
Its formulation contains clinically studied probiotics like Lactobacillus rhamnosus GG, proven to help ease occasional tummy troubles and reduce fussiness caused by colic.
Plus, it’s safe for daily use in infants from birth to 12 months, supporting healthy development in the crucial early months.
While the dropper could be a bit easier to use, its gentle ingredients and trusted reputation make it a reliable go-to for soothing your little one’s stomach.
Be sure to also check out the best probiotic for iron absorption for more options! Also, here is the price history so you know exactly when to buy!
Mommy's Bliss Probiotic for Colic
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| Supports digestion |
| Recommended by pediatricians |
| Easy to administer |
Mommy's Bliss Baby Probiotic Drops Everyday is trusted by pediatricians and easy for parents to incorporate into daily routines.
Its gentle liquid form makes administering to little ones a breeze, which is a huge plus during those hectic colic moments.
While some babies might experience minor gas, most find the drops soothing over time.
The small bottle size means it’s convenient to carry around, making it perfect for on-the-go use.
Overall, this probiotic strikes a lovely balance between effectiveness and simplicity, helping to support your baby's digestive health with minimal fuss.
Be sure to also check out the best probiotic for low fodmap for more options! Also, here is the price history so you know exactly when to buy!
BioGaia Protectis Baby
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| Relieves colic symptoms |
| Safe for newborns |
| Naturally found in breast milk |
BioGaia Baby has a proven track record spanning over 20 years for soothing fussiness, colic, and gas in infants.
Its gentle, scientifically validated probiotic is naturally found in breast milk, making it a trusted choice for parents seeking safe relief from digestive discomfort.
Ideal for newborns from day one, it helps calm crying, fussiness, and gassiness without the use of artificial ingredients.
While it’s on the pricier side and dosing can require some attention, its safety profile and efficacy make it a stand-out option for a happy, comfortable tummy.
Be sure to also check out the best probiotic for bv for more options! Also, here is the price history so you know exactly when to buy!
Culturelle Probiotics for Babies
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| Helps soothe baby |
| Supports digestive health |
| Easy to administer |
Culturelle Baby Colic plus offers a safe and gentle solution tailored specifically for little ones.
Its probiotic strains work naturally to help reduce fussiness and crying caused by digestive upset, providing quick comfort.
Plus, it includes 100% of the daily vitamin D needs, supporting your baby's bone strength and immune health. Ease of use is a big plus—just five drops a day, directly into the mouth or a bottle, makes life easier for busy parents.
While the bottle is small and can leak during travel, its trusted ingredients and proven benefits make it a top contender for calming babies with colic.
Be sure to also check out the best probiotics for sleep for more options! Also, here is the price history so you know exactly when to buy!
MaryRuth Organics Baby Probiotic Drops Probiotic for Colic
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| Clinically studied strains |
| Supports colic symptoms |
| Organic & Non-GMO |
MaryRuth's Organic Infant Probiotic Drops contain a carefully selected blend of clinically studied strains like Pediococcus pentosaceus and Bifidobacterium longum, which are shown to support gut health and reduce colic symptoms.
The organic, non-GMO, and allergen-free formula makes it a safe choice for delicate newborns.
While the application can be a bit messy due to its greasy consistency, many parents appreciate the ease of adding just a few drops to their baby's daily routine.
Overall, a solid, gentle option to help soothe your little one's fussiness.
Be sure to also check out the best probiotic for hemorrhoids for more options! Also, here is the price history so you know exactly when to buy!
Mylicon
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| Reduces crying fussiness |
| Supports immune health |
| Easy to use |
Infants' Mylicon Daily Probiotic Drops are a game-changer for fussier little ones.
They effectively reduce crying and fussiness when used daily, giving parents much-needed relief.
Beyond soothing, these drops support a healthy gut and boost immune defenses—super important for growing infants.
They're versatile and easy to incorporate into a feeding routine: add to breastmilk, formula, or apply directly.
Plus, they’re free from common allergens and artificial ingredients, making them a safe choice.
The only minor hiccup?
They require refrigeration and a fresh start every 28 days, but the benefits for your baby's well-being make it worth it.
Be sure to also check out the best probiotics for gallbladder for more options! Also, here is the price history so you know exactly when to buy!
Wellements Baby Probiotic
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| Supports digestive health |
| Easy to administer drops |
| Certified organic ingredients |
Wellements Organic Probiotic Drops make supporting your little one's gut health simple and stress-free.
Crafted from high-quality, certified organic ingredients like LactoSpore Bacillus coagulans and organic MCT oil, they are gentle yet powerful.
The odorless, tasteless drops easily mix into feeds, making administration a breeze—no fuss, no mess.
While it’s on the pricier side and requires refrigeration, the peace of mind knowing you're giving a clean, allergen-free product makes it worthwhile.
For parents seeking a reliable, no-nonsense probiotic, these drops are a solid choice to soothe colic and promote overall healthy digestion.
Be sure to also check out the best probiotic for fertility for more options! Also, here is the price history so you know exactly when to buy!
Mommy's Bliss Probiotic for Colic
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| Easy to administer |
| Tasteless drops |
| Supports digestion |
Mommy's Bliss Baby Probiotic Drops + Vitamin D are gentle, safe, and easy to use — perfect for delicate baby tummies.
Since they’re tasteless and come in a liquid drop form, administering them is a breeze, and parents won't have to wrestle with unpleasant flavors.
The probiotic strain used is one of the most researched, giving us peace of mind that it’s effective for supporting digestion.
While the limited reviews mean we recommend caution, its pediatrician approval and reputation for calming colic make it a top contender for new parents seeking quick, reliable relief.
Be sure to also check out the best probiotic for prostate for more options! Also, here is the price history so you know exactly when to buy!








