Top 13 Supplements for Gut Motility You Must Try

Discover the best supplements for gut motility to enhance digestion and comfort. Quick, effective options for a healthier, happier gut.
BrandMy RatingPrice
Enzymedica
Most Cost-Effective
8.6/10
Enzyme Science
Best for Gentle Support
7.4/10
Enzymedica
Best for Regularity
8.2/10
Thorne
Best for Digestive Comfort
8.8/10
Integrative Therapeutics
7.8/10

Best Supplements for Gut Motility

Struggling with sluggish digestion or unpredictable gut feelings? Dive into our curated guide of the best supplements for gut motility, where vibrant ingredients and innovative formulas work together to turn your digestive chain into a smooth, well-oiled machine. Discover how a few targeted additions can transform your gut health from sluggish to superb.

Most Cost-Effective: Enzymedica Digest Gold

Enzymedica Digest Gold + ATPro, Maximum Strength Enzyme Formula, Prevents Bloating and Gas, 14 Key Enzymes Including Amylase, Protease, Lipase and Lactase, 21 Capsules
Highlights
Effective digestion support
Reduces bloating and gas
Supports nutrient absorption

It offers a full-strength, high-potency enzyme blend at a price that won't break the bank, making it our top choice for "Most Cost-Effective".

The Thera-blend enzymes are formulated for maximum activity across different pH levels, ensuring you get faster relief and better digestion after those hearty meals.

Plus, just one capsule a day can help break down up to 86g of carbs, 16g of protein, and 34g of fat—perfect for keeping bloating and gas at bay.

While some users report mild discomfort or decreased effectiveness over time, overall, it provides excellent digestive support for those seeking an affordable, reliable option.

Be sure to also check out the best supplement for flexibility for more options! Also, here is the price history so you know exactly when to buy!

Price history for Enzymedica Digest Gold on Amazon

Best for Gentle Support: Enzyme Science GI Motility Complex

GI Motility Complex, 60 Capsules – All Natural Digestive Enzyme Support – Gut Health Supplement– Supports Gastrointestinal Motility and Transport – Aids Small Bowel and Stomach
Highlights
Helps with regularity
Reduces bloating
Supports digestion

It offers gentle yet effective support thanks to its unique ProDigest blend with triple standardized artichoke and ginger.

This combo works wonders in the small bowel and stomach, improving nutrient transit times without the harshness of laxatives.

Plus, the inclusion of Apple Cider Vinegar with the "Mother" boosts overall digestive health.

It’s an excellent choice for those seeking regularity and bloating reduction without uncomfortable side effects.

Just keep in mind that some users may experience gas, and the price could be a bit steep.

Overall, a smart, supportive option for your gut health!

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Price history for Enzyme Science GI Motility Complex on Amazon

Best for Regularity: Enzymedica Gut Motility

Enzymedica, Gut Motility, Promotes Regular, Healthy Bowel Movements, Reduces Occasional Bloating & Constipation, 30 Count
Highlights
Supports normal gut transit
Clinically studied ingredients
Gentle digestive support

specifically formulated to promote regularity and healthy bowel movements, it combines a clinically studied blend of artichoke and ginger that gently supports digestion.

The ProDigest blend works harmoniously with your body to improve gut motility, making it our top pick for "Best for Regularity." Plus, the addition of apple cider vinegar with the "Mother" helps balance your digestive pH and boosts metabolism.

Just two capsules a day before your largest meals make this supplement simple to incorporate into your routine.

While results can vary and may take a few weeks, it's a gentle, science-backed option worth trying.

Be sure to also check out the best supplement for methylation for more options! Also, here is the price history so you know exactly when to buy!

Price history for Enzymedica Gut Motility on Amazon

Best for Digestive Comfort: Thorne GI Relief

THORNE GI Relief - Digestion Supplement Supports Gut Health & Bloating Relief - Made with Marshmallow Root Extract & Digestive Enzymes - 180 Capsules - 90 Servings
Highlights
Soothes digestive discomfort
No laxative effect
High-quality ingredients

It’s specially formulated for digestive comfort, thanks to soothing marshmallow root and slippery elm that calm irritation and support motility.

The addition of organic aloe vera provides gentle relief without the harsh laxative effects, making it a safe choice for daily use.

Plus, the DGL licorice keeps potential blood pressure concerns at bay.

Overall, it’s a high-quality, allergen-free option for those seeking to ease discomfort and promote better gut function—just note, it may not work for everyone and can be on the pricier side.

Be sure to also check out the best supplements for postpartum hormones for more options! Also, here is the price history so you know exactly when to buy!

Price history for Thorne GI Relief on Amazon

Integrative Therapeutics Motility Activator

Integrative Therapeutics Motility Activator - Supports Gastrointestinal Motility and Transport* - Gut Health Support for Men and Women with Ginger Root and Artichoke Leaf Extract* - 60 Capsules
Highlights
Effective, real results
Contains natural extracts
Vegan and gluten-free

The Motility Activator by Integrative Therapeutics harnesses a powerful blend of ginger and artichoke leaf extracts to give your gut the support it needs.

Many users report noticeable improvements in gastrointestinal transit and regularity, making it a promising option for those looking to enhance gut health naturally.

Plus, its vegan and gluten-free formula ensures it fits into a variety of diets.

While some find it pricey or report inconsistent results, the natural ingredients and proven efficacy make it worth considering.

Just remember to chat with your healthcare provider to ensure it’s right for you.

Be sure to also check out the best supplements for myelin sheath repair for more options! Also, here is the price history so you know exactly when to buy!

Price history for Integrative Therapeutics Motility Activator on Amazon

Pure Encapsulations MotilPro

Pure Encapsulations MotilPro | Hypoallergenic Dietary Supplement to Promote Healthy Gut Motility* | 180 Capsules
Highlights
Supports healthy gut motility
High-quality, pure ingredients
Effective for SIBO motility

Its powerful support for healthy gut motility really stands out.

The combination of 5-HTP and ginger promotes proper serotonin function, aiding in smoother gastric emptying and better intestinal transit—great for anyone experiencing sluggish digestion or SIBO concerns.

Plus, with acetyl L-carnitine, it nurtures neuronal health, supporting those nerve signals that keep your gut moving.

Quality is front and center—all ingredients are premium, pure, and free from unnecessary additives.

While the price may be steep and the serving size a bit inconvenient, the effectiveness makes it a compelling choice for those prioritizing gut health.

Be sure to also check out the best supplement for booty growth for more options! Also, here is the price history so you know exactly when to buy!

Price history for Pure Encapsulations MotilPro on Amazon

Vitanica Supplements for Gut Motility

Vitanica, Colon Motility Blend, Colon Support, Vegan, 90 Capsules
Highlights
Supports gentle colon cleansing
Contains natural herbal ingredients
Enhances digestive fluid secretion

It offers comprehensive colon support by blending gentle stimulants with herbal tonics, making it suitable for those seeking a natural, balanced approach.

The inclusion of magnesium helps soften stool and promote movement, while the bitter herbs enhance digestive fluid secretion, aiding overall gut motility.

Although results may take a few weeks and some users might experience mild stomach upset initially, its natural ingredients and targeted formula make it a reliable choice for long-term gut health.

Consistent use ensures you’re supporting your digestive system naturally and effectively.

Be sure to also check out the best supplement for veins for more options! Also, here is the price history so you know exactly when to buy!

Price history for Vitanica on Amazon

Pure Encapsulations G.I. Fortify

Pure Encapsulations G.I. Fortify (Capsules) | Supports G.I. Function, Motility and Detoxification | 120 Capsules
Highlights
Supports bowel regularity
Enhances colon health
Pure, high-quality ingredients

G.

I.

Fortify capsules are a gentle yet effective way to support your gut's natural rhythm.

Packed with psyllium and flax, it helps maintain regular bowel movements without any fuss.

Plus, it promotes detoxification and microflora balance, which are key for overall gut health.

We also love that it’s made from premium, pure ingredients—free from unnecessary additives and common allergens.

Keep in mind, some users experience initial dry mouth, and results may take a few weeks.

Still, if you're after a clean, trustworthy supplement to support your colon, this one’s worth trying.

Be sure to also check out the best supplements for spleen health for more options! Also, here is the price history so you know exactly when to buy!

Price history for Pure Encapsulations G.I. Fortify on Amazon

Silver Fern

Silver Fern Brand Motility- Non-Laxative Constipation and Slow Motility Boost - 60 Capsules, 30 Day Supply - Contains Artichoke Leaf, Tender Okra Pods, & Winter Cherry
Highlights
Contains natural ingredients
Good for daily use
Supports gut health

Motility by Silver Fern Brand leverages natural ingredients like French artichoke leaf extract, tender okra pods, and winter cherry to support gut motility.

It’s designed for daily use and works best when taken consistently, ideally with your first meal.

Some users report seeing results within 2-3 weeks, but patience is key—give it at least a month to notice full benefits.

Keep in mind, experiences vary, and some may find it worsens symptoms.

Overall, if you're searching for a gentle, plant-based option, this supplement is worth considering.

Be sure to also check out the best supplement for dog incontinence for more options! Also, here is the price history so you know exactly when to buy!

Price history for Silver Fern on Amazon

Emma Gut Health Supplements for Gut Motility

Emma Gut Health - 2 Pack - Gas and Bloating Relief, Constipation, Leaky Gut Repair - Gut Cleanse & Restore Digestion - Regulate Bowel Movement. Probiotics and Laxative Alternative, 120 Capsules
Highlights
Effective digestion support
Natural ingredients used
Relieves bloating and gas

Its effective digestion support noticeably reduces bloating and gas, helping you go about your day with confidence.

Made from natural ingredients, it offers a gentle yet powerful way to normalize bathroom habits without relying on harsh laxatives.

Plus, it targets the root cause of sluggish digestion, promoting long-term gut health instead of quick fixes.

While some may find it a bit pricey and needing consistent use, the benefits—like clearer skin, boosted metabolism, and more energy—make it worth the wait.

A truly science-backed game-changer for gut motility.

Be sure to also check out the best supplement for dog dementia for more options! Also, here is the price history so you know exactly when to buy!

Price history for Emma Gut Health on Amazon

Zenwise Digestive Enzymes

Zenwise Health Digestive Enzymes and Bromelain for Gut Health - Probiotic Multi Enzymes with Prebiotics and Probiotics for Women and Men for Digestive Health and Bloating Relief for Digestion - 60 CT
Highlights
Fast, noticeable relief
Supports gut health
Plant-based enzymes

The 3-in-1 formula delivers rapid relief by combining powerful lab-proven enzymes like bromelain and papain that start working immediately, breaking down food up to 39% more completely.

The inclusion of proven probiotics guarantees they arrive alive and begin supporting your gut health within hours—crucial for nutrient absorption.

Plus, the plant-based enzymes and prebiotics nourish your microbiome and support regularity naturally.

It’s a playful yet effective approach to maintaining optimal digestion.

While it requires daily use and may cause mild bloating initially, it’s a solid choice for gut support on the go.

Be sure to also check out the best supplements for spider veins for more options! Also, here is the price history so you know exactly when to buy!

Price history for Zenwise Digestive Enzymes on Amazon

Ancient Nutrition SBO Probiotics

Probiotics by Ancient Nutrition, SBO Probiotics Gut Restore 60 Ct, Promotes Gut Health, Digestive and Immune Support, Gluten Free, Ancient Superfoods Blend, 25 Billion CFUs* Per Serving
Highlights
Supports gut health
Contains 25 Billion CFU
Organic fermented superfoods

Ancient Nutrition's SBO Gut Restore blends soil-based probiotics with organic fermented superfoods, creating a potent combo for supporting gut health.

With 25 billion CFU, it packs a punch, helping balance your digestive system and boost immunity with just two capsules a day.

We love that it's formulated with clinically-studied, backed ingredients, and produced in the USA for quality assurance.

While the capsules might be a bit tough to swallow and the price could be a consideration for daily use, its focus on both digestive wellness and immune support makes it a solid choice for anyone seeking gut motility help.

Be sure to also check out the best supplement for bigger loads for more options! Also, here is the price history so you know exactly when to buy!

Price history for Ancient Nutrition SBO Probiotics on Amazon

Nature's Sunshine Supplements for Gut Motility

Nature's Sunshine Lower Bowel Stimulator - Helps Relieve Constipation - Cleanse & Detox Your Colon with Natural Herbal Ingredients - 25 Servings - 100 Vegcaps
Highlights
Effective natural relief
Gentle on stomach
Trusted for decades

Nature's Sunshine Lower Bowel Stimulator combines time-tested herbs like cascara sagrada, buckthorn, and turkey rhubarb to deliver effective, natural relief without harsh chemicals.

Its gentle approach helps soothe the digestive tract with ginger and licorice root, making it suitable for daily use.

While it may take a few days to see full results and requires some dosage tweaking, its trustworthy legacy of over 50 years and solid reviews make it a reliable choice.

If you want gentle, natural support for regularity, this product deserves a spot on your shortlist.

Be sure to also check out the best supplement for healing after surgery for more options! Also, here is the price history so you know exactly when to buy!

Price history for Nature's Sunshine on Amazon

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