Best Probiotic Drops for Newborns
Navigating the world of newborn probiotics can feel like charting a course through uncharted waters, where every drop counts toward your baby's health and happiness. Finding the perfect probiotic drops ensures gentle, effective support for your little one's tiny tummy, making every choice both effortless and impactful. Dive into our curated list of the best probiotic drops designed to nurture your newborn from the very first sip.
Most Wallet-Friendly: MaryRuth Organics Probiotic Drops

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Supports infant digestion |
Organic and Non-GMO |
Easy to administer |
The MaryRuth Organics USDA Organic Infant Liquid Probiotic Drops deliver amazing value without sacrificing quality.
Formulated with a blend of five probiotic strains, it’s designed specifically for your baby’s delicate tummy, supporting digestion and overall gut health.
The unflavored, liquid form makes administration straightforward — simply dispense a few drops directly or mix with a beverage.
Plus, with just 100 CFU per dose, it’s gentle yet effective.
Best of all, it’s certified organic, vegan, and free from common allergens, making it a versatile choice for health-conscious parents.
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Best for Colic Relief: BioGaia

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Relieves colic & gas |
Safe for newborns |
Naturally found in breast milk |
This probiotic drops stand out: bioGaia Protectis Baby has been clinically studied for soothing colic and digestive discomfort, making it a trusted choice for new parents.
It’s suitable from the very first day of life, and works naturally in the gut to reduce fussiness, gas, and spit-up.
Plus, since it contains probiotics naturally found in breast milk, it's a gentle, safe option without allergens, dairy, or artificial ingredients.
While it may take a few days to see full results and requires careful dosing, its proven safety and effectiveness make it a top pick for colic relief.
Be sure to also check out the best probiotics for tonsil stones for more options! Also, here is the price history so you know exactly when to buy!

Best for Digestive Support: BioGaia Protectis Baby

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Relieves Colic & Gas |
Safe for Newborns |
Contains Breast Milk Probiotics |
BioGaia Protectis Baby Probiotic Drops with Vitamin D is our top pick for digestive support because it really works to soothe crying, fussing, colic, and gas — proven by over 20 years of research.
It’s completely safe for newborns from day one, whether they’re breast-fed or bottle-fed, and contains probiotics naturally found in breast milk.
Plus, it’s free from allergens, artificial ingredients, and sugars, keeping it wholesome and gentle.
The only downsides?
It’s a bit pricey, and some parents find administering drops tricky.
Still, a fantastic choice for a happy, happier baby!
Be sure to also check out the best probiotics for dental health for more options! Also, here is the price history so you know exactly when to buy!

Best for Gentle On Newborns: Mommy's Bliss Probiotic

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Supports digestive health |
Pediatrician recommended |
Easy squeeze dropper |
Mommy's Bliss Baby Probiotic Drops are specifically designed to be gentle on newborns, making them our top pick for the "Best for Gentle On Newborns" category.
Pediatrician-approved and containing the world’s most researched probiotic strain, they support your baby's digestive health safely from day one.
The easy squeeze dropper simplifies dosing, and the liquid format absorbs quickly into tiny tummies.
While some babies might dislike the taste or the packaging’s susceptibility to melting if exposed to heat, overall, these drops deliver a reliable, doctor-recommended solution to keep your little one's gut happy and healthy.
Be sure to also check out the best probiotics for sleep for more options! Also, here is the price history so you know exactly when to buy!

Lovebug Probiotics

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Includes vitamin D |
Improves digestion |
Convenient and easy |
Lovebug Probiotics are formulated specifically for little ones aged 0 to 12 months, addressing common issues like colic and digestive upset with six clinically studied strains.
We love that they’re USDA Organic Certified and sugar-free, ensuring maximum benefit without artificial fillers—no allergens, chemicals, or preservatives in sight.
The award-winning reputation and positive reviews speak volumes about their quality and effectiveness.
Plus, the inclusion of vitamin D adds extra support for immune health.
While the drops dispense quickly and lack a dropper, their convenience and natural ingredients make them a solid choice for new parents seeking a trustworthy probiotic.
Be sure to also check out the best probiotics for alcohol drinkers for more options! Also, here is the price history so you know exactly when to buy!

Wellements Baby Probiotic

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Supports digestive health |
Gently formulated |
Easy to administer |
Wellements' Organic Probiotic Drops are a gentle, effective choice for supporting your baby’s gut and immune health.
Made with high-quality probiotic LactoSpore and organic MCT oil, they’re certified organic and free from all the usual suspects like artificial colors or preservatives.
The drops are odorless and tasteless, making administration super easy—just a few drops on a nipple, pacifier, or mixed with breast milk.
While the price might make you pause, the peace of mind that comes with a safe, natural product is priceless for parents seeking the best for their little ones.
Be sure to also check out the best probiotic with butyrate for more options! Also, here is the price history so you know exactly when to buy!

Mommy's Bliss Probiotic Drops for Newborns

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Easy to administer |
Taste-free, gentle |
Supports digestion |
Mommy's Bliss Baby Probiotic Drops + Vitamin D stand out for their gentle formula and the fact that they use the most researched probiotic strain, ensuring safety and efficacy for your little one.
The drops are taste-free and super easy to administer, which makes giving daily probiotics hassle-free for parents.
While the glass bottle requires careful handling, its compact size makes it perfect for on-the-go use.
Keep in mind, it might take a few hours to see the full benefits, but overall, it’s a reliable, pediatrician-recommended choice that supports a happy, healthy tummy from day one.
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Culturelle

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Clinically studied probiotics |
Gentle, safe ingredients |
Eases infant fussiness |
Culturelle Baby Digestive Calm + Comfort Drops is the #1 pediatrician-recommended probiotic for a reason.
Its formula contains two of the most clinically studied strains, making it a trustworthy choice for parents looking to support their baby’s gut health.
We love how gentle yet effective it is—helping to ease fussiness and colic naturally.
Plus, it's easy to administer, whether on a spoon, bottle, or directly in the mouth, which makes those nightly fusses a little easier to handle.
Just a heads-up: the dropper could be more ergonomic, and careful dose adjustments are needed.
Overall, a safe, reliable option for daily use.
Be sure to also check out the best mineral drops for water for more options! Also, here is the price history so you know exactly when to buy!

Culturelle Baby Probiotics

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Clinically studied probiotics |
Gentle, safe ingredients |
Supports digestion & immunity |
Culturelle Baby Immune & Digestive Support Probiotic + Vitamin D Drops is pediatrician-recommended, giving parents peace of mind.
The formula contains two of the most clinically studied probiotics for infants—Lactobacillus rhamnosus GG and other gentle ingredients—making it safe and effective for babies 0-12 months.
The added Vitamin D helps boost immunity and overall health.
It’s easy to give—just a few drops a day—though the small bottle means you might need to refill more often.
Overall, a trusted choice for nurturing your baby’s early development naturally.
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Pink Stork Probiotic Drops for Newborns

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Supports healthy digestion |
Easy to administer |
Vegan and non-GMO |
Pink Stork's Baby Probiotic Drops deliver a powerful punch of 1 billion CFU of Lactobacillus rhamnosus per serving, making it a top-tier choice for supporting your baby’s gut health.
The no-drip syringe makes administering a simple task, whether added to food or milk.
Plus, it’s vegan, non-GMO, and free from artificial flavors, giving you peace of mind.
While some users have reported partial leakage and the effectiveness can vary, it remains a favorite for parents seeking a clean, reliable probiotic.
A true baby must-have!
Be sure to also check out the best prohormone stack for more options! Also, here is the price history so you know exactly when to buy!

Mylicon

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Reduces fussiness effectively |
Supports immune health |
Easy to add to bottles |
Infants' Mylicon Daily Probiotic Drops are a game-changer for fussiness and colic.
Clinically proven to reduce crying, these drops help soothe your baby naturally.
They also support a healthy gut and immune system by replenishing beneficial bacteria — a huge plus for those battling antibiotics or digestive issues.
Plus, they’re incredibly versatile — just add a few drops to a bottle or apply directly on the breast.
Safe and free from common allergens, these drops are a reliable choice for parents wanting a gentle, effective probiotic option.
Be sure to also check out the best additive for noisy lifters for more options! Also, here is the price history so you know exactly when to buy!

MaryRuth Organics Baby Probiotic Drops

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Supports infant gut health |
Gentle, easy to administer |
Certified USDA Organic |
MaryRuth's Organic Infant Probiotic Drops are a gentle, effective choice for supporting your baby's delicate digestive system.
The blend of clinically studied strains like Pediococcus pentosaceus and Bifidobacterium longum targets common issues like colic by helping to reduce fussiness and improve stool consistency.
Plus, with a clean label—certified USDA Organic, vegan, and allergen-free—it ticks all the boxes for health-conscious parents.
While the liquid can be a bit messy and the cap tends to clog, the overall benefits and ease of use make it a top contender for soothing your little one naturally.
Be sure to also check out the best prohormone for muscle growth for more options! Also, here is the price history so you know exactly when to buy!

Culturelle Probiotics Probiotic Drops for Newborns

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Supports Digestive Health |
Easy to Administer |
Contains Vitamin D |
Culturelle Baby Colic plus Soothing Probiotic Drops offers a gentle yet effective way to support your little one's digestive health.
Formulated with safe, natural probiotic strains, it helps reduce fussiness and soothe tummy troubles, making it a go-to for many new parents.
Plus, it includes 100% of the daily vitamin D needed for strong bone development.
The easy-to-use dropper makes administration a breeze—just five drops a day!
While the small bottle size and price might be drawbacks, its support for gut health and immune boost truly stand out.
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